Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367137 | 0.90 | ALOX5 (0.40) | MAOBMMP2MMP9MMP12ALDH1A1 | |
| SCHEMBL364734 | 0.90 | LMNA (0.40) | MAOBMMP2MMP9MMP12MAPT | |
| SCHEMBL365618 | 0.89 | L3MBTL1 (0.39) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL365578 | 0.86 | KMT2A (0.53) | MAOBMMP2MMP9MMP12MAPT | |
| SCHEMBL364182 | 0.85 | MAOB (0.46) | MAOBMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL365359 | 0.85 | ALDH1A1 (0.47) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL364902 | 0.84 | ALDH1A1 (0.40) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL365200 | 0.84 | TP53 (0.40) | MAOBMMP2MMP9MMP12MAPT | |
| SCHEMBL366107 | 0.84 | MAPT (0.39) | MAOBMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL364749 | 0.82 | ESR1 (0.38) | MMP2MMP9MMP12MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |