Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365200 | 0.90 | TP53 (0.40) | ALOX5MMP1MMP2MMP9MMP12 | |
| SCHEMBL365618 | 0.90 | L3MBTL1 (0.39) | KDM4EMEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL365579 | 0.90 | MAOB (0.38) | MMP2MMP9MMP12KDM4EMEN1 | |
| SCHEMBL367136 | 0.86 | KMT2A (0.52) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL364902 | 0.85 | ALDH1A1 (0.40) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL365494 | 0.85 | CASP3 (0.39) | MMP1MMP2MMP9MMP12KDM4E | |
| SCHEMBL364734 | 0.85 | LMNA (0.40) | MMP1MMP2MMP9MMP12KDM4E | |
| SCHEMBL366340 | 0.83 | MAOB (0.49) | ALOX5GID4RXRARXRBRXRG | |
| SCHEMBL364749 | 0.83 | ESR1 (0.38) | MMP1MMP2MMP9MMP12KDM4E | |
| SCHEMBL365753 | 0.82 | ALDH1A1 (0.35) | KDM4EMEN1ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |