Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365618 | 0.92 | L3MBTL1 (0.39) | MAPTKMT2AGAAL3MBTL1ALDH1A1 | |
| SCHEMBL367137 | 0.90 | ALOX5 (0.40) | KMT2ASMN1; SMN2MAOAMAOBALOX5 | |
| SCHEMBL364734 | 0.90 | LMNA (0.40) | TP53MAPTKMT2ASMN1; SMN2MAOB | |
| SCHEMBL364902 | 0.86 | ALDH1A1 (0.40) | MAPTKMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL365494 | 0.86 | CASP3 (0.39) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL365199 | 0.85 | KMT2A (0.55) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL365579 | 0.84 | MAOB (0.38) | MAPTKMT2AMAOBL3MBTL1ALDH1A1 | |
| SCHEMBL365753 | 0.84 | ALDH1A1 (0.35) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL365359 | 0.83 | ALDH1A1 (0.47) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL366794 | 0.83 | PSEN1 (0.36) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |