Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366821 | 0.92 | AGTR1 (0.41) | EGFRAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL367256 | 0.88 | EGFR (0.40) | EGFRAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL365771 | 0.88 | EGFR (0.43) | EGFRALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL366790 | 0.87 | EGFR (0.41) | EGFRAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL366559 | 0.83 | ATM (0.47) | EGFRALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL365023 | 0.82 | EGFR (0.40) | EGFRAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL367222 | 0.79 | EGFR (0.41) | EGFRPOLBSRCBAZ2BBAZ2A | |
| SCHEMBL366876 | 0.78 | EGFR (0.44) | EGFRAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL366116 | 0.76 | CA1 (0.41) | EGFRAGTR1 | |
| SCHEMBL365213 | 0.76 | PKM (0.39) | EGFRALDH1A1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |