Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL367741 | 0.88 | LMNA (0.44) | LMNAKDM4EHPGDALDH1A1NPSR1 | |
| SCHEMBL365666 | 0.87 | HPGD (0.52) | KDM4EHPGDALDH1A1EGFRSRC | |
| SCHEMBL365750 | 0.87 | POLB (0.46) | LMNAKDM4EHPGDALDH1A1EGFR | |
| SCHEMBL366536 | 0.86 | EGFR (0.53) | KDM4EHPGDALDH1A1EGFRSRC | |
| SCHEMBL366371 | 0.82 | EGFR (0.45) | KDM4EHPGDALDH1A1EGFRSRC | |
| SCHEMBL365935 | 0.81 | KDM4E (0.47) | KDM4EHPGDALDH1A1EGFRSRC | |
| SCHEMBL31060260 | 0.81 | KDM4E (0.45) | LMNAKDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL365908 | 0.81 | KDM4E (0.45) | LMNAKDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL366784 | 0.78 | SCN9A (0.50) | EGFRSRCAGTR1SCN9A | |
| SCHEMBL364296 | 0.77 | ALDH1A1 (0.49) | LMNAKDM4EHPGDALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007008-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |