SCHEMBL3659587

SCHEMBL3659587

Brc1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.68
MAPK1 P28482 1/20 0.68
NPC1 O15118 1/20 0.48
NFKB1 P19838 1/20 0.48
RAB9A P51151 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
CYP1A2 P05177 2/20 0.48
CYP3A4 P08684 2/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP2D6 P10635 1/20 0.48
MAPT P10636 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
NR1H4 Q96RI1 1/20 0.41
MEN1 O00255 1/20 0.41
CRHBP P24387 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3660659 1.00 ALDH1A1 (0.68) ALDH1A1MAPK1NPC1NFKB1RAB9A
SCHEMBL17165569 1.00 ALDH1A1 (0.68) ALDH1A1MAPK1NPC1NFKB1RAB9A
SCHEMBL15907007 1.00 ALDH1A1 (0.68) ALDH1A1MAPK1NPC1NFKB1RAB9A
SCHEMBL13854644 1.00 ALDH1A1 (0.68) ALDH1A1MAPK1NPC1NFKB1RAB9A
SCHEMBL17165567 1.00 ALDH1A1 (0.68) ALDH1A1MAPK1NPC1NFKB1RAB9A
SCHEMBL74527 0.98 ALDH1A1 (0.64) ALDH1A1MAPK1NPC1NFKB1RAB9A
SCHEMBL13969319 0.98 ALDH1A1 (0.64) ALDH1A1MAPK1NPC1NFKB1RAB9A
SCHEMBL4237094 0.98 ALDH1A1 (0.64) ALDH1A1MAPK1NPC1NFKB1RAB9A
SCHEMBL20664596 0.98 ALDH1A1 (0.64) ALDH1A1MAPK1NPC1NFKB1RAB9A
SCHEMBL12156927 0.98 ALDH1A1 (0.71) ALDH1A1MAPK1NPC1NFKB1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113443997-B Aromatic amine derivative organic electroluminescent material and device thereof 北京夏禾科技有限公司 2024-02-27 CN disclosed
US-11778901-B2 Organic electroluminescent material and organic electroluminescent device comprising same SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-03 US disclosed
US-11778901-B2 Organic electroluminescent material and organic electroluminescent device comprising same SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-03 US disclosed
CN-111187199-B Carbazole derivative, and light-emitting element, light-emitting device, and electronic device using carbazole derivative 株式会社半导体能源研究所 2023-07-21 CN disclosed
CN-116375628-A Carbazole derivative, and light-emitting element, light-emitting device, and electronic device using carbazole derivative 株式会社半导体能源研究所 2023-07-04 CN disclosed
CN-116375629-A Carbazole derivative, and light-emitting element, light-emitting device, and electronic device using carbazole derivative 株式会社半导体能源研究所 2023-07-04 CN disclosed
EP-3282496-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-04-26 EP disclosed
EP-3671885-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2023-03-01 EP disclosed
US-20220388958-A1 CARBAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-12-08 US disclosed
EP-3229284-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-08-31 EP disclosed
US-20160118591-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2016-04-28 US disclosed
EP-2757094-A1 Carbazole derivative, and light-emitting element, light-emitting device, and electronic device uing carbazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-23 EP disclosed
EP-2225204-B1 CARBAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2014-04-23 EP disclosed
EP-2225204-A1 CARBAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING CARBAZOLE DERIVATIVE Semiconductor Energy Laboratory Co, Ltd. (JP) 2010-09-08 EP disclosed
US-20090160323-A1 Carbazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-06-25 US disclosed
WO-2009072587-A1 CARBAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING CARBAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-06-11 WO disclosed
US-20090115320-A1 AROMATIC TRIAMINE COMPOUND AND ORGANIC ELECTTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-05-07 US disclosed
US-20090115320-A1 AROMATIC TRIAMINE COMPOUND AND ORGANIC ELECTTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-05-07 US disclosed
US-7425654-B2 Aromatic triamine compound and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2008-09-16 US disclosed
US-7425654-B2 Aromatic triamine compound and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2008-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388958-A1 CARBAZOLE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC DEVICE USING CARBAZOLE DERIVATIVE CRY1, AP3D1, AHR ALDH1A1 133/4885MAPK1 1317/4885NPC1 3803/4885
US-20090115320-A1 AROMATIC TRIAMINE COMPOUND AND ORGANIC ELECTTROLUMINESCENCE DEVICE USING THE SAME EML4, ACVRL1, APOL1 ALDH1A1 1929/4885MAPK1 2518/4885NPC1 4488/4885
US-11778901-B2 Organic electroluminescent material and organic electroluminescent device comprising same MAOA, AOC1, AOC2 ALDH1A1 67/4885MAPK1 789/4885NPC1 3457/4885
US-20090160323-A1 Carbazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Carbazole Derivative CRY1, AP3D1, AHR ALDH1A1 133/4885MAPK1 1317/4885NPC1 3803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.