Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.62 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.62 |
| ▸ | CASP7 | P55210 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660785 | 0.99 | TTR (0.60) | TTRALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL15799958 | 0.88 | MEN1 (0.47) | TTRALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL8996372 | 0.81 | TTR (0.65) | TTRALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL6901828 | 0.81 | PGAM1 (0.51) | TTRALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL16950304 | 0.79 | PGAM1 (0.50) | TTRALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL18048116 | 0.78 | ALDH1A1 (0.71) | TTRALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL17038035 | 0.77 | MAOA (0.65) | TTRALDH1A1MAPTHPGDMEN1 | |
| Rhein SCHEMBL29404324 | 0.77 | ALDH1A1 (1.00) | TTRALDH1A1MAPTHPGDMEN1 | |
| Rhein SCHEMBL25253 | 0.77 | ALDH1A1 (1.00) | TTRALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL3660783 | 0.76 | PKLR (0.46) | TTRALDH1A1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150011636-A1 | METHOD FOR TREATMENT OF DISEASES WITH DIOXOANTHRACENE SULPHONATE DERIVATIVES | LABORATOIRE MEDIDOM SA (CH) | 2015-01-08 | — | — | US | disclosed |
| US-20150011636-A1 | METHOD FOR TREATMENT OF DISEASES WITH DIOXOANTHRACENE SULPHONATE DERIVATIVES | LABORATOIRE MEDIDOM SA (CH) | 2015-01-08 | — | — | US | disclosed |
| US-20150011636-A1 | METHOD FOR TREATMENT OF DISEASES WITH DIOXOANTHRACENE SULPHONATE DERIVATIVES | LABORATOIRE MEDIDOM SA (CH) | 2015-01-08 | — | — | US | disclosed |
| US-8754128-B2 | Dioxoanthracene sulphonate derivatives | LABORATOIRE MEDIDOM SA (CH) | 2014-06-17 | — | — | US | disclosed |
| US-8754128-B2 | Dioxoanthracene sulphonate derivatives | LABORATOIRE MEDIDOM SA (CH) | 2014-06-17 | — | — | US | disclosed |
| US-8754128-B2 | Dioxoanthracene sulphonate derivatives | LABORATOIRE MEDIDOM SA (CH) | 2014-06-17 | — | — | US | disclosed |
| EP-2220036-B1 | DIOXOANTHRACENE SULPHONATE DERIVATIVES | MEDIDOM LAB (CH) | 2012-12-26 | — | — | EP | disclosed |
| US-20110054032-A1 | DIOXOANTHRACENE SULPHONATE DERIVATIVES | LABORATOIRE MEDIDOM SA (CH) | 2011-03-03 | — | — | US | disclosed |
| US-20110054032-A1 | DIOXOANTHRACENE SULPHONATE DERIVATIVES | LABORATOIRE MEDIDOM SA (CH) | 2011-03-03 | — | — | US | disclosed |
| US-20110054032-A1 | DIOXOANTHRACENE SULPHONATE DERIVATIVES | LABORATOIRE MEDIDOM SA (CH) | 2011-03-03 | — | — | US | disclosed |
| EP-2220036-A1 | DIOXOANTHRACENE SULPHONATE DERIVATIVES | LABORATOIRE MEDIDOM S.A. (CH) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009063427-A1 | DIOXOANTHRACENE SULPHONATE DERIVATIVES | LABORATOIRE MEDIDOM S.A. (CH) | 2009-05-22 | — | — | WO | disclosed |
| EP-2060562-A1 | Dioxoanthracene sulphonate derivatives | LABORATOIRE MEDIDOM S.A. (CH) | 2009-05-20 | — | — | EP | disclosed |
| EP-2060562-A1 | Dioxoanthracene sulphonate derivatives | LABORATOIRE MEDIDOM S.A. (CH) | 2009-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054032-A1 | DIOXOANTHRACENE SULPHONATE DERIVATIVES | DECR1, SUCNR1, RELA | TTR 3903/4885ALDH1A1 1157/4885MAPT 4641/4885 |
| US-20150011636-A1 | METHOD FOR TREATMENT OF DISEASES WITH DIOXOANTHRACENE SULPHONATE DERIVATIVES | DECR1, GRHPR, DECR2 | TTR 1552/4885ALDH1A1 1003/4885MAPT 4615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.