Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365494 | 0.88 | CASP3 (0.39) | MAPTL3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL365359 | 0.88 | ALDH1A1 (0.47) | MAPTL3MBTL1TSHRKDM4EALDH1A1 | |
| SCHEMBL364902 | 0.86 | ALDH1A1 (0.40) | MAPTL3MBTL1TSHRKDM4EALDH1A1 | |
| SCHEMBL364734 | 0.86 | LMNA (0.40) | MAPTL3MBTL1TSHRKDM4EALDH1A1 | |
| SCHEMBL365618 | 0.86 | L3MBTL1 (0.39) | MAPTL3MBTL1TSHRKDM4EALDH1A1 | |
| SCHEMBL366106 | 0.85 | ALDH1A1 (0.55) | MAPTL3MBTL1TSHRKDM4EALDH1A1 | |
| SCHEMBL365579 | 0.84 | MAOB (0.38) | MAPTL3MBTL1TSHRKDM4EALDH1A1 | |
| SCHEMBL366244 | 0.84 | PSEN1 (0.41) | MAPTL3MBTL1TSHRKDM4EALDH1A1 | |
| SCHEMBL366935 | 0.84 | ALDH1A1 (0.39) | MAPTL3MBTL1TSHRKDM4EALDH1A1 | |
| SCHEMBL364973 | 0.83 | KMT2A (0.42) | MAPTL3MBTL1TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |