SCHEMBL366586

SCHEMBL366586

C=CCNCc1cccc(CNCC=C)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.40
DPP7 Q9UHL4 1/20 0.39
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
PKM P14618 1/20 0.38
ALOX12 P18054 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
BCHE P06276 2/20 0.38
SLC2A4 P14672 1/20 0.38
CXCR4 P61073 1/20 0.38
KDM4E B2RXH2 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18235905 0.87 SLC6A2 (0.45) ALDH1A1LMNATDP1CXCR4KDM4E
SCHEMBL29536299 0.87 SLC2A4 (0.56) LMNAMAPTPKMKMT2ASLC2A4
SCHEMBL29536361 0.87 CHRM2 (0.59) CHRM2LMNA
SCHEMBL16641037 0.86 BCHE (0.44) CHRM2ALDH1A1BCHECXCR4KDM4E
SCHEMBL681149 0.84 MEN1 (0.56) CHRM2DPP7ALDH1A1MAPTMEN1
Ammonia Solution, Strong SCHEMBL27753398 0.83 MEN1 (0.54) CHRM2DPP7ALDH1A1MAPTMEN1
Water SCHEMBL3478298 0.83 MEN1 (0.54) CHRM2DPP7ALDH1A1MAPTMEN1
Hydrochloric Acid SCHEMBL250190 0.83 MEN1 (0.54) CHRM2DPP7ALDH1A1MAPTPKM
Bromide SCHEMBL9394202 0.83 MEN1 (0.54) CHRM2DPP7ALDH1A1MAPTMEN1
SCHEMBL25175588 0.82 CHRM2 (0.60) CHRM2ALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11643580-B2 Method for strengthening of metal structures using toughened 2C-epoxy adhesives SIKA TECHNOLOGY AG (CH) 2023-05-09 US disclosed
US-20220227991-A1 TOUGHENED TWO-COMPONENT EPOXY COMPOSITION SIKA TECHNOLOGY AG (CH) 2022-07-21 US disclosed
EP-3494152-B1 POLYMER BLENDS FOR EPOXY RESINS COMPOSITIONS SIKA TECH AG (CH) 2022-04-27 EP disclosed
US-20210198537-A1 METHOD FOR STRENGTHENING OF METAL STRUCTURES USING TOUGHENED 2C-EPOXY ADHESIVES SIKA TECHNOLOGY AG (CH) 2021-07-01 US disclosed
US-20210078903-A1 EPOXY RESIN COMPOSITION FOR UNDERWATER GROUTING SIKA TECHNOLOGY AG (CH) 2021-03-18 US disclosed
EP-3677648-A1 PROCESS FOR DETECTING WEAR IN FLOOR COATING SYSTEMS AND COMPOSITIONS THEREOF SIKA TECHNOLOGY AG (CH) 2020-07-08 EP disclosed
US-20190300697-A1 POLYMER BLENDS FOR EPOXY RESINS COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2019-10-03 US disclosed
EP-3168256-B1 EYEWEAR MATERIAL COMPRISING A POLYURETHANE RESIN, EYEWEAR FRAME AND LENS MITSUI CHEMICALS INC (JP) 2019-08-07 EP disclosed
EP-3494152-A1 POLYMER BLENDS FOR EPOXY RESINS COMPOSITIONS Sika Technology AG (CH) 2019-06-12 EP disclosed
EP-2776489-B1 EPOXY RESIN CURING AGENT WITH AROMATIC AMINO GROUPS SIKA TECH AG (CH) 2019-03-27 EP disclosed
US-20110166259-A1 WATER SOLUBLE AMINE AND USES THEREOF SIKA TECHNOLOGY AG (CH) 2011-07-07 US disclosed
US-20110130479-A1 ADHESION PROMOTER COMPOUNDS FOR OILED STEEL SIKA TECHNOLOGY AG (CH) 2011-06-02 US disclosed
US-20110082248-A1 POLYAMINE HAVING A REDUCED BLUSHING EFFECT, AND USE THEREOF AS A CURING AGENT FOR EPOXY RESINS SIKA TECHNOLOGY AG (CH) 2011-04-07 US disclosed
US-20100323202-A1 USE OF CARBOXYLIC ACID HYDRAZIDE FOR DE-BONDING POLYURETHANE ADHESIVES SIKA TECHNOLOGY AG (CH) 2010-12-23 US disclosed
US-20100190014-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2010-07-29 US disclosed
US-20100101455-A1 ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE SIKA TECHNOLOGY AG (CH) 2010-04-29 US disclosed
US-7629433-B2 Odor-less during hydrolytic deblocking, separation; for use as source for aldehydes; crosslinking agents SIKA TECHNOLOGY AG (CH) 2009-12-08 US disclosed
US-20090176944-A1 Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof SIKA TECHNOLOGY AG (CH) 2009-07-09 US disclosed
US-20090099333-A1 Compounds Containing Aldimine SIKA TECHNOLOGY AG (CH) 2009-04-16 US disclosed
US-20070055038-A1 Adducts containing isocyanate groups and composition adhering effectively to painted substrates SIKA TECHNOLOGY AG (CH) 2007-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130479-A1 ADHESION PROMOTER COMPOUNDS FOR OILED STEEL ELL, MED1, HSF1 CHRM2 4177/4885DPP7 4877/4885ALDH1A1 269/4885
US-20110082248-A1 POLYAMINE HAVING A REDUCED BLUSHING EFFECT, AND USE THEREOF AS A CURING AGENT FOR EPOXY RESINS SRM, PRMT1, PBRM1 CHRM2 3147/4885DPP7 4547/4885ALDH1A1 287/4885
US-20100190014-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE ADH5, ADH1A, ADH1C CHRM2 1861/4885DPP7 4364/4885ALDH1A1 6/4885
US-20100101455-A1 ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE ALDH7A1, ILK, ALDH3A1 CHRM2 1206/4885DPP7 4186/4885ALDH1A1 5/4885
US-20090176944-A1 Aldimines Comprising Reactive Groups Containing Active Hydrogen, and Use Thereof ADH5, ADH1C, ADH1A CHRM2 1328/4885DPP7 4172/4885ALDH1A1 5/4885
US-20090099333-A1 Compounds Containing Aldimine ALDH7A1, ALDH3A1, ALDH1A1 CHRM2 2299/4885DPP7 3471/4885ALDH1A1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.