Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pendimethalin SCHEMBL21821 | 0.92 | L3MBTL1 (0.49) | HCAR3L3MBTL1CYP1A2ALDH1A1CYP3A4 | |
| Pendimethalin SCHEMBL8373915 | 0.92 | L3MBTL1 (0.49) | HCAR3L3MBTL1CYP1A2ALDH1A1CYP3A4 | |
| Pendimethalin SCHEMBL14690957 | 0.92 | L3MBTL1 (0.49) | HCAR3L3MBTL1CYP1A2ALDH1A1CYP3A4 | |
| Pendimethalin SCHEMBL29392877 | 0.92 | L3MBTL1 (0.49) | HCAR3L3MBTL1CYP1A2ALDH1A1CYP3A4 | |
| Pendimethalin SCHEMBL27926297 | 0.91 | L3MBTL1 (0.48) | HCAR3L3MBTL1CYP1A2ALDH1A1CYP3A4 | |
| Pendimethalin SCHEMBL20723668 | 0.91 | L3MBTL1 (0.48) | HCAR3L3MBTL1CYP1A2ALDH1A1CYP3A4 | |
| Pendimethalin SCHEMBL8057686 | 0.91 | L3MBTL1 (0.48) | HCAR3L3MBTL1CYP1A2ALDH1A1CYP3A4 | |
| Pendimethalin SCHEMBL28241258 | 0.86 | ALDH1A1 (0.44) | HCAR3L3MBTL1CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL9240963 | 0.85 | HCAR3 (0.43) | HCAR3L3MBTL1CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL11525932 | 0.85 | L3MBTL1 (0.45) | HCAR3L3MBTL1CYP1A2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531670-B1 | HERBICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-09 | — | — | EP | disclosed |
| US-8551918-B2 | Herbicidal composition | SYNGENTA CROP PROTECTION LLC (US) | 2013-10-08 | — | — | US | disclosed |
| US-8097561-B2 | Herbicidal composition | SYNGENTA CROP PROTECTION, INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-20070197387-A1 | Herbicidal Composition | SYNGENTA PARTICIPATIONS AG (CH) | 2007-08-23 | — | — | US | disclosed |
| EP-1689227-A2 | HERBICIDAL COMPOSITION | Syngenta Participations AG (CH) | 2006-08-16 | — | — | EP | disclosed |
| EP-1531670-A4 | HERBICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2005-11-23 | — | — | EP | disclosed |
| US-20050233907-A1 | Herbicidal composition | SYNGENTA CROP PROTECTION AG (CH) | 2005-10-20 | — | — | US | disclosed |
| WO-2005055716-A2 | HERBICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-23 | — | — | WO | disclosed |
| EP-1531670-A1 | HERBICIDAL COMPOSITION | Syngenta Participations AG (CH) | 2005-05-25 | — | — | EP | disclosed |
| WO-2003105587-A1 | HERBICIDAL COMPOSITION | SYNGENTA PARTICIPATIONS AG (CH) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050233907-A1 | Herbicidal composition | ADH5, ADH1C, AQP3 | HCAR3 12/4885L3MBTL1 2230/4885CYP1A2 83/4885 |
| US-20070197387-A1 | Herbicidal Composition | DDT, HDHD5, DERL1 | HCAR3 306/4885L3MBTL1 1819/4885CYP1A2 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.