Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 3/20 | 0.33 |
| ▸ | FNTB | P49356 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 6/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.31 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367175 | 0.77 | HTR7 (0.39) | IDO1PTGS2TACR1ALDH1A1 | |
| SCHEMBL367204 | 0.75 | RORC (0.43) | IDO1PTGS2TACR1FNTAFNTB | |
| SCHEMBL366827 | 0.68 | KMT2A (0.45) | SRCMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL371112 | 0.67 | IDO1 (0.51) | IDO1PTGS2TACR1FNTAFNTB | |
| SCHEMBL366461 | 0.67 | HTT (0.46) | IDO1PTGS2EGFRMEN1KMT2A | |
| SCHEMBL366789 | 0.66 | IDO1 (0.38) | IDO1PTGS2TACR1FNTAFNTB | |
| SCHEMBL366887 | 0.66 | KDM4E (0.56) | IDO1PTGS2FNTAFNTBEGFR | |
| SCHEMBL365934 | 0.66 | KDM4E (0.45) | IDO1PTGS2FNTAFNTBEGFR | |
| SCHEMBL365778 | 0.66 | EGFR (0.42) | IDO1PTGS2FNTAFNTBEGFR | |
| SCHEMBL366875 | 0.66 | EGFR (0.42) | IDO1PTGS2FNTAFNTBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |