Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.39 |
| ▸ | HTR6 | P50406 | 12/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | HTR1D | P28221 | 4/20 | 0.38 |
| ▸ | HTR1B | P28222 | 4/20 | 0.38 |
| ▸ | HTR1F | P30939 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367176 | 0.78 | HTR6 (0.38) | HTR7HTR6PTGS2HTR1AHTR1D | |
| SCHEMBL367174 | 0.77 | IDO1 (0.37) | PTGS2TACR1ALDH1A1IDO1 | |
| SCHEMBL367204 | 0.74 | RORC (0.43) | PTGS2TACR1ALDH1A1IDO1 | |
| SCHEMBL366132 | 0.70 | ALDH1A1 (0.38) | HTR7HTR6PTGS2HTR1AHTR1D | |
| SCHEMBL366535 | 0.70 | EGFR (0.48) | ALDH1A1IDO1 | |
| SCHEMBL366827 | 0.67 | KMT2A (0.45) | ALDH1A1CYP1A2POLB | |
| SCHEMBL365387 | 0.67 | ALDH1A1 (0.46) | ALDH1A1CYP1A2POLB | |
| SCHEMBL371112 | 0.67 | IDO1 (0.51) | PTGS2TACR1ALDH1A1CYP1A2POLB | |
| SCHEMBL366461 | 0.66 | HTT (0.46) | PTGS2ALDH1A1IDO1 | |
| SCHEMBL366789 | 0.65 | IDO1 (0.38) | PTGS2TACR1ALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |