Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.38 |
| ▸ | HTR7 | P34969 | 7/20 | 0.38 |
| ▸ | HTR1A | P08908 | 5/20 | 0.38 |
| ▸ | HTR1D | P28221 | 5/20 | 0.38 |
| ▸ | HTR1B | P28222 | 4/20 | 0.38 |
| ▸ | HTR1F | P30939 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366789 | 0.82 | IDO1 (0.38) | PTGS2ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL366033 | 0.79 | NPC1 (0.40) | PTGS2ALDH1A1KDM4EMAPTIDO1 | |
| SCHEMBL367175 | 0.78 | HTR7 (0.39) | HTR6HTR7HTR1AHTR1DHTR1B | |
| SCHEMBL367204 | 0.77 | RORC (0.43) | PTGS2ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL364537 | 0.71 | BAZ2B (0.38) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL365387 | 0.71 | ALDH1A1 (0.46) | ALDH1A1CYP1A2POLBKDM4EMEN1 | |
| SCHEMBL366817 | 0.69 | NPC1 (0.39) | ALDH1A1KDM4EMAPT | |
| SCHEMBL365916 | 0.69 | KDM4E (0.40) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL366820 | 0.68 | IDO1 (0.43) | PTGS2ALDH1A1POLBKDM4EMAPT | |
| SCHEMBL365788 | 0.68 | BAZ2B (0.45) | PTGS2KDM4EIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |