Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10375234 | 0.75 | PTPN1 (0.38) | PTPN1MAPT | |
| SCHEMBL5598585 | 0.69 | — | — | |
| SCHEMBL15965807 | 0.67 | ENO1 (0.31) | PTPN1 | |
| SCHEMBL10454020 | 0.67 | MAPT (0.31) | MAPT | |
| SCHEMBL5104625 | 0.67 | MAPT (0.31) | MAPT | |
| SCHEMBL15659901 | 0.65 | ALDH1A1 (0.30) | — | |
| SCHEMBL10454019 | 0.65 | — | — | |
| SCHEMBL13736883 | 0.65 | — | — | |
| SCHEMBL14113511 | 0.64 | TP53 (0.32) | PTPN1MAPT | |
| SCHEMBL22556904 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630491-B2 | Production of 2,2,4,4-tetramethylcyclobutane-1,3-diol from secondary alcohols and 2,2,4,4-tetramethylcyclobutanedione using homogeneous catalysts | EASTMAN CHEMICAL COMPANY (US) | 2026-05-19 | — | — | US | claimed |
| US-12577184-B2 | Production of 2,2,4,4-tetramethylcyclobutane-1,3-diol from isobutanol using a homogeneous catalyst | EASTMAN CHEMICAL COMPANY (US) | 2026-03-17 | — | — | US | claimed |
| EP-4255873-B1 | PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM ISOBUTANOL USING A HOMOGENEOUS CATALYST | EASTMAN CHEM CO (US) | 2024-12-18 | — | — | EP | claimed |
| EP-4255881-B1 | PRODUCTION OF 2,2,4, 4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM SECONDARY ALCOHOLS AND 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIONE USING HOMOGENEOUS CATALYSTS | EASTMAN CHEM CO (US) | 2024-12-18 | — | — | EP | claimed |
| US-20230406792-A1 | PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1,3-DIOL FROM SECONDARY ALCOHOLS AND 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIONE USING HOMOGENEOUS CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2023-12-21 | — | — | US | claimed |
| US-20230399278-A1 | PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1,3-DIOL FROM ISOBUTANOL USING A HOMOGENEOUS CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2023-12-14 | — | — | US | claimed |
| EP-4255873-A1 | PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM ISOBUTANOL USING A HOMOGENEOUS CATALYST | Eastman Chemical Company (US) | 2023-10-11 | — | — | EP | claimed |
| EP-4255881-A1 | PRODUCTION OF 2,2,4, 4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM SECONDARY ALCOHOLS AND 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIONE USING HOMOGENEOUS CATALYSTS | Eastman Chemical Company (US) | 2023-10-11 | — | — | EP | claimed |
| WO-2022119792-A1 | PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM ISOBUTANOL USING A HOMOGENEOUS CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2022-06-09 | — | — | WO | claimed |
| WO-2022119793-A1 | PRODUCTION OF 2,2,4, 4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM SECONDARY ALCOHOLS AND 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIONE USING HOMOGENEOUS CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2022-06-09 | — | — | WO | claimed |
| EP-3362499-A1 | SYSTEMS AND METHODS FOR FORMING POLYURETHANES | Eastman Chemical Company (US) | 2018-08-22 | — | — | EP | claimed |
| EP-3230242-A1 | BATCH PROCESS FOR THE PREPARATION OF CIS-2,2,4,4-TETRAMETHYLCYCLOBUTANE-1,3-DIOL | Eastman Chemical Company (US) | 2017-10-18 | — | — | EP | claimed |
| EP-3230241-A1 | PROCESS FOR THE PREPARATION OF CIS-2,2,4,4-TETRAMETHYLCYCLOBUTANE-1,3-DIOL | Eastman Chemical Company (US) | 2017-10-18 | — | — | EP | claimed |
| WO-2017066142-A1 | SYSTEMS AND METHODS FOR FORMING POLYURETHANES | EASTMAN CHEMICAL COMPANY (US) | 2017-04-20 | — | — | WO | claimed |
| US-20170101502-A1 | SYSTEMS AND METHODS FOR FORMING POLYURETHANES | EASTMAN CHEMICAL COMPANY (US) | 2017-04-13 | — | — | US | claimed |
| WO-2016094478-A1 | PROCESS FOR THE PREPARATION OF CIS-2,2,4,4-TETRAMETHYLCYCLOBUTANE-1,3-DIOL | EASTMAN CHEMICAL COMPANY (US) | 2016-06-16 | — | — | WO | claimed |
| WO-2016094479-A1 | BATCH PROCESS FOR THE PREPARATION OF CIS-2,2,4,4-TETRAMETHYLCYCLOBUTANE-1,3-DIOL | EASTMAN CHEMICAL COMPANY (US) | 2016-06-16 | — | — | WO | claimed |
| US-9238603-B1 | Batch process for the preparation of cis-2,2,4,4-tetramethylcyclobutane-1,3-diol | EASTMAN CHEMICAL COMPANY (US) | 2016-01-19 | — | — | US | claimed |
| US-9238602-B1 | Process for the preparation of cis-2,2,4,4-tetramethylcyclobutane-1,3-diol | EASTMAN CHEMICAL COMPANY (US) | 2016-01-19 | — | — | US | claimed |
| EP-1011952-B1 | LIGHTWEIGHT BOTTLES AND METHOD FOR MAKING SAME | EASTMAN CHEM CO (US) | 2002-08-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399278-A1 | PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1,3-DIOL FROM ISOBUTANOL USING A HOMOGENEOUS CATALYST | TDO2, HAO2, CYP8B1 | PTPN1 4843/4885MAPT 3776/4885 |
| US-12630491-B2 | Production of 2,2,4,4-tetramethylcyclobutane-1,3-diol from secondary alcohols and 2,2,4,4-tetramethylcyclobutanedione using homogeneous catalysts | ADH1C, ADH1A, ADH5 | PTPN1 4469/4885MAPT 3682/4885 |
| US-20230406792-A1 | PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1,3-DIOL FROM SECONDARY ALCOHOLS AND 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIONE USING HOMOGENEOUS CATALYSTS | ADH1C, ADH1A, ADH5 | PTPN1 4793/4885MAPT 3099/4885 |
| US-12577184-B2 | Production of 2,2,4,4-tetramethylcyclobutane-1,3-diol from isobutanol using a homogeneous catalyst | HAO2, TDO2, THRB | PTPN1 4737/4885MAPT 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.