Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3684935 | 0.83 | LMNA (0.50) | LMNAKDM4ECYP2C19ELANETSHR | |
| SCHEMBL15657717 | 0.75 | LMNA (0.43) | LMNAELANEATM | |
| SCHEMBL3682464 | 0.75 | LMNA (0.35) | LMNAKDM4ECYP2C19TSHRNPSR1 | |
| SCHEMBL820210 | 0.71 | CTSD (0.32) | — | |
| SCHEMBL3626473 | 0.71 | CTSD (0.32) | — | |
| SCHEMBL15659871 | 0.69 | LMNA (0.39) | LMNAELANE | |
| SCHEMBL3677973 | 0.67 | LMNA (0.38) | LMNAKDM4ECYP2C19TSHRNPSR1 | |
| SCHEMBL31509083 | 0.65 | LMNA (0.78) | LMNAKDM4ECYP2C19ELANETSHR | |
| SCHEMBL18663145 | 0.63 | ELANE (0.48) | LMNAKDM4ECYP2C19ELANETSHR | |
| SCHEMBL379582 | 0.63 | LMNA (0.39) | LMNAKDM4ECYP2C19ELANETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250109245-A1 | PREPARATION OF UNSATURATED POLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 2025-04-03 | — | — | US | disclosed |
| EP-4473036-A1 | PREPARATION OF UNSATURATED POLYESTERS | Eastman Chemical Company (US) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023147330-A1 | PREPARATION OF UNSATURATED POLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-2912095-B1 | COPOLYESTERS CONTAINING NEOPENTYL GLYCOL AND 2,2,4,4-TETRAALKYL-1,3-CYCLOBUTANEDIOL | EASTMAN CHEM CO (US) | 2018-11-14 | — | — | EP | disclosed |
| EP-2734566-B1 | SULFOPOLYESTER POLYMER COMPOSITIONS WITH IMPROVED WATER DISPERSIBILITY | EASTMAN CHEM CO (US) | 2016-11-02 | — | — | EP | disclosed |
| US-20160280956-A1 | SULFOPOLYESTER POLYMER COMPOSITIONS WITH IMPROVED WATER DISPERSIBILITY | EASTMAN CHEMICAL COMPANY (US) | 2016-09-29 | — | — | US | disclosed |
| US-9127122-B2 | Copolyesters containing neopentyl glycol and 2,2,4,4-tetraalkyl 1,3-cyclobutanediol | EASTMAN CHEMICAL COMPANY (US) | 2015-09-08 | — | — | US | disclosed |
| EP-2912095-A1 | COPOLYESTERS CONTAINING NEOPENTYL GLYCOL AND 2,2,4,4-TETRAALKYL-1,3-CYCLOBUTANEDIOL | Eastman Chemical Company (US) | 2015-09-02 | — | — | EP | disclosed |
| EP-2734566-A1 | SULFOPOLYESTER POLYMER COMPOSITIONS WITH IMPROVED WATER DISPERSIBILITY | Eastman Chemical Company (US) | 2014-05-28 | — | — | EP | disclosed |
| WO-2014066296-A1 | COPOLYESTERS CONTAINING NEOPENTYL GLYCOL AND 2,2,4,4-TETRAALKYL-1,3-CYCLOBUTANEDIOL | EASTMAN CHEMICAL COMPANY (US) | 2014-05-01 | — | — | WO | disclosed |
| US-7838707-B2 | for a specific cis:trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters; hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione from the pyrolysis of isobutyric anhydride and dimerization of the resulting dimethylketene | EASTMAN CHEMICAL COMPANY (US) | 2010-11-23 | — | — | US | disclosed |
| US-7582804-B2 | by hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione; cesium and cobalt promoters; specific cis/trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters | EASTMAN CHEMICAL COMPANY (US) | 2009-09-01 | — | — | US | disclosed |
| US-7560600-B2 | by hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione in the presence of an zirconium-promoted nickel-based catalyst; specific cis/trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters | EASTMAN CHEMICAL COMPANY (US) | 2009-07-14 | — | — | US | disclosed |
| US-7524994-B2 | by hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione; specific cis/trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters | EASTMAN CHEMICAL COMPANY (US) | 2009-04-28 | — | — | US | disclosed |
| US-7521583-B2 | Process for the preparation of tetraalkylcyclobutane-1,3-diol in the presence of a cobalt-based catalyst | EASTMAN CHEMICAL COMPANY (US) | 2009-04-21 | — | — | US | disclosed |
| US-20080154069-A1 | for a specific cis:trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters; hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione from the pyrolysis of isobutyric anhydride and dimerization of the resulting dimethylketene | EASTMAN CHEMICAL COMPANY (US) | 2008-06-26 | — | — | US | disclosed |
| US-20080132742-A1 | by hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione; cesium and cobalt promoters; specific cis/trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters | EASTMAN CHEMICAL COMPANY (US) | 2008-06-05 | — | — | US | disclosed |
| US-20080132737-A1 | by hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione; specific cis/trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters | EASTMAN CHEMICAL COMPANY (US) | 2008-06-05 | — | — | US | disclosed |
| US-20080132738-A1 | by hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione in the presence of an zirconium-promoted nickel-based catalyst; specific cis/trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters | EASTMAN CHEMICAL COMPANY (US) | 2008-06-05 | — | — | US | disclosed |
| US-20080132739-A1 | PROCESS FOR THE PREPARATION OF TETRAALKYLCYCLOBUTANE-1,3-DIOL IN THE PRESENCE OF A COBALT-BASED CATALYST | EASTMAN CHEMICAL COMPANY (US) | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132739-A1 | PROCESS FOR THE PREPARATION OF TETRAALKYLCYCLOBUTANE-1,3-DIOL IN THE PRESENCE OF A COBALT-BASED CATALYST | TET1, TET3, HPD | LMNA 4417/4885KDM4E 689/4885CYP2C19 2932/4885 |
| US-20080132738-A1 | by hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione in the presence of an zirconium-promoted nickel-based catalyst; specific cis/trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters | ZRANB2, RCC1, TELO2 | LMNA 4321/4885KDM4E 2176/4885CYP2C19 3254/4885 |
| US-20080132742-A1 | by hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione; cesium and cobalt promoters; specific cis/trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters | CA3, TELO2, CA1 | LMNA 4600/4885KDM4E 1638/4885CYP2C19 2714/4885 |
| US-20080154069-A1 | for a specific cis:trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters; hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione from the pyrolysis of isobutyric anhydride and dimerization of the resulting dimethylketene | CA3, CA1, CA2 | LMNA 4357/4885KDM4E 1682/4885CYP2C19 2766/4885 |
| US-20080132737-A1 | by hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione; specific cis/trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters | TELO2, CA3, CA1 | LMNA 4675/4885KDM4E 2310/4885CYP2C19 3769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.