SCHEMBL1492149

SCHEMBL1492149

CO[Si](OC)(OC)C(C)c1ccccc1CNC(C)N

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
KDM4E B2RXH2 2/20 0.33
POLB P06746 2/20 0.33
CASR P41180 1/20 0.32
ALDH1A1 P00352 2/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 2/20 0.31
MAPK1 P28482 1/20 0.31
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9480548 0.79 CHRM2 (0.45) POLBALDH1A1MAPTTDP1BCHE
SCHEMBL3679833 0.79 PNMT (0.35)
SCHEMBL28350065 0.77 L3MBTL1 (0.37) L3MBTL1KDM4EALDH1A1GAAMAPT
SCHEMBL28936286 0.77 MAPT (0.37) ATML3MBTL1POLBMAPT
SCHEMBL139764 0.76 NPBWR1 (0.33) ALDH1A1
SCHEMBL29393805 0.76 NPBWR1 (0.33) ALDH1A1
SCHEMBL2111676 0.76 IDO1 (0.35)
SCHEMBL3653474 0.75 ATM (0.36) ATML3MBTL1KDM4EPOLBCASR
SCHEMBL139734 0.74 GABRA1 (0.36) KDM4EPOLBALDH1A1MAPTTDP1
Hydrochloric Acid SCHEMBL2158165 0.74 ALDH1A1 (0.36) ATML3MBTL1KDM4EPOLBCASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910076-B1 POLYMER INTERLAYERS COMPRISING POLY(CYCLOHEXANEDIMETHYLENE TEREPHTHALATE-CO-ETHYLENE TEREPHTHALATE) COPOLYESTER SOLUTIA INC (US) 2016-10-05 EP claimed
US-8309615-B2 Aqueous silica dispersion ROHM AND HAAS COMPANY (US) 2012-11-13 US claimed
EP-1910076-A1 POLYMER INTERLAYERS COMPRISING POLY(CYCLOHEXANEDIMETHYLENE TEREPHTHALATE-CO-ETHYLENE TEREPHTHALATE) COPOLYESTER Solutia Inc. (US) 2008-04-16 EP claimed
WO-2007005711-A1 POLYMER INTERLAYERS COMPRISING POLY(CYCLOHEXANEDIMETHYLENE TEREPHTHALATE-CO-ETHYLENE TEREPHTHALATE) COPOLYESTER SOLUTIA INC. (US) 2007-01-11 WO claimed
US-20070003746-A1 Polymer interlayers comprising poly(cyclohexanedimethylene terephthalate-co-ethylene terephthalate) copolyester SOLUTIA, INC. 2007-01-04 US claimed
US-20060178452-A1 Aqueous silica dispersion ROHM AND HAAS COMPANY 2006-08-10 US claimed
US-4950583-A ADJUVANT POLYMERS AND ALKOXY SILANES BREWER SCIENCE INC. (US) 1990-08-21 US claimed
EP-0260976-A2 Adhesion promoting product and process for treating an integrated circuit substrate therewith Brewer Science, Inc. (US) 1988-03-23 EP claimed
EP-1910076-B1 POLYMER INTERLAYERS COMPRISING POLY(CYCLOHEXANEDIMETHYLENE TEREPHTHALATE-CO-ETHYLENE TEREPHTHALATE) COPOLYESTER SOLUTIA INC (US) 2016-10-05 EP disclosed
US-9353226-B2 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates made therefrom and use of the polymers and condensates Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2016-05-31 US disclosed
EP-2343544-B1 Method for analyzing hemoglobin by electrophoresis ARKRAY INC (JP) 2015-03-11 EP disclosed
US-8702941-B2 Method of analyzing hemoglobin by electrophoresis ARKARY, Inc. (JP) 2014-04-22 US disclosed
US-20140088279-A1 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates made therefrom and use of the polymers and condensates Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2014-03-27 US disclosed
US-8309615-B2 Aqueous silica dispersion ROHM AND HAAS COMPANY (US) 2012-11-13 US disclosed
EP-0619532-A2 Fusing components containing ceramer compositions XEROX CORPORATION (US) 1994-10-12 EP disclosed
US-5337129-A Intermediate transfer component coatings of ceramer and grafted ceramer XEROX CORPORATION (US) 1994-08-09 US disclosed
WO-1993011190-A1 POLYMER NANOCOMPOSITES FORMED BY MELT PROCESSING OF A POLYMER AND AN EXFOLIATED LAYERED MATERIAL DERIVATIZED WITH REACTIVE ORGANO SILANES ALLIED-SIGNAL INC. (US) 1993-06-10 WO disclosed
EP-0432921-A1 Water-based composites with superior cure in thick films, and chemical and shock resistance ROHM AND HAAS COMPANY (US) 1991-06-19 EP disclosed
EP-0432920-A2 Polymer-modified cements with improved chemical resistance ROHM AND HAAS COMPANY (US) 1991-06-19 EP disclosed
US-5017632-A Overlay for portland cement, floors ROHM AND HAAS COMPANY (US) 1991-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140088279-A1 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates made therefrom and use of the polymers and condensates AS3MT, TST, ALG3 ATM 1496/4885L3MBTL1 2253/4885KDM4E 4773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.