SCHEMBL36846

SCHEMBL36846

C=C(C=CC(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
HCAR2 Q8TDS4 4/20 0.37
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL4359365 0.94 LMNA (0.37) TSHRTP53EGLN1EGLN3HCAR2
Acrylic Acid Methyl Ester SCHEMBL4677730 0.87 HCAR2 (0.44) HCAR2ALDH1A1ALOX15RECQLHSD17B10
Maleic Acid SCHEMBL31299770 0.83 ALDH1A1 (0.39) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL27566573 0.81 CTSK (0.32) DGAT1
SCHEMBL7871608 0.78 TSHR (0.41) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL1327371 0.78 HCAR2 (0.31) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL7164500 0.78 POLB (0.31) TSHRTP53EGLN1EGLN3HCAR2
SCHEMBL27544622 0.78
SCHEMBL28332775 0.77 TAS1R3 (0.35) ALDH1A1
SCHEMBL36949 0.76 HCAR2 (0.52) TSHRTP53EGLN1EGLN3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070166269-A1 Cosmetic composition containing a statistical polymer with a linear chain of ethylenic nature L'OREAL (FR) 2007-07-19 US claimed
US-20070092473-A1 Cosmetic composition containing a statistical polymer with a linear main chain of ethylenic nature L'OREAL (FR) 2007-04-26 US claimed
WO-2019028248-A1 SYSTEMS AND METHODS FOR IMPROVING DELIVERY OF TOPICAL ACTIVES YOUNG PHARMACEUTICALS, INC. (US) 2019-02-07 WO disclosed
CN-105828880-A Hair fixatives including starch ester based polyglucose polymers 阿克苏诺贝尔化学品国际有限公司 2016-08-03 CN disclosed
CN-105813623-A Hair fixatives including cellulose ether based polyglucose polymers 阿克苏诺贝尔化学品国际有限公司 2016-07-27 CN disclosed
CN-105813693-A Hair fixatives including cellulose ester based polyglucose polymers 阿克苏诺贝尔化学品国际有限公司 2016-07-27 CN disclosed
EP-2380917-B1 ACTIVE ENERGY BEAM CURABLE RESIN COMPOSITION JUJO PAPER CO LTD (JP) 2015-09-09 EP disclosed
US-8748507-B2 Active energy ray curable resin composition NIPPON PAPER CHEMICALS CO., LTD. (JP) 2014-06-10 US disclosed
US-20110274941-A1 ACTIVE ENERGY RAY CURABLE RESIN COMPOSITION NIPPON PAPER CHEMICALS CO., LTD. (JP) 2011-11-10 US disclosed
EP-2380917-A1 ACTIVE ENERGY BEAM CURABLE RESIN COMPOSITION Nippon Paper Chemicals Co., Ltd. (JP) 2011-10-26 EP disclosed
CN-102043333-A Photosensitive resin composition, method for producing cured film, cured film, organic el display device and liquid crystal display device FUJIFILM CORP 2011-05-04 CN disclosed
CN-1157179-C Personal care compositions comprising linear toughened silicone grafted polymers ���޿��غ͸ʱ�����˾ 2004-07-14 CN disclosed
CN-1102041-C Hair styling composition contg. non-silicone and silicone grafted polymers and low level of voltile hydrocarbon solvent PROCTER & GAMBLE (US) 2003-02-26 CN disclosed
CN-1322265-A Wrinkle reducing composition PROCTER & GAMBLE (US) 2001-11-14 CN disclosed
CN-1284856-A Personal care compositions PROCTER & GAMBLE (US) 2001-02-21 CN disclosed
CN-1284853-A Personal care compositions suitable for hair styling PROCTER & GAMBLE (US) 2001-02-21 CN disclosed
CN-1260711-A Personal care composation containing linear toughened silicone grafted polymers PROCTER & GAMBLE (US) 2000-07-19 CN disclosed
CN-1259862-A Personal care compositions containing toughened grafted polymers PROCTER & GAMBLE (US) 2000-07-12 CN disclosed
CN-1200664-A Hair styling composition contg. non-silicone and silicone grafted polymers and low level of voltile hydrocarbon solvent PROCTER & GAMBLE (US) 1998-12-02 CN disclosed
US-5665337-A GRAFTED POLYSILOXANE ADDITION-CONDENSATION COPOLYMER; RINSE-OFF HAIR CONDITIONERS THE PROCTER & GAMBLE COMPANY (US) 1997-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070166269-A1 Cosmetic composition containing a statistical polymer with a linear chain of ethylenic nature POLH, LAGE3, ELOVL6 TSHR 2900/4885TP53 122/4885EGLN1 1292/4885
US-20070092473-A1 Cosmetic composition containing a statistical polymer with a linear main chain of ethylenic nature H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TELO2, METTL14 TSHR 1287/4885TP53 312/4885EGLN1 1130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.