Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.68 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410252 | 0.86 | IDO1 (0.58) | ACHEKMT2ATAAR1IDO1CYP3A4 | |
| SCHEMBL1149394 | 0.86 | IDO1 (0.58) | ACHEKMT2ATAAR1IDO1CYP3A4 | |
| SCHEMBL1468357 | 0.86 | IDO1 (0.58) | LMNATAAR1IDO1LOXL2CYP3A4 | |
| SCHEMBL16561361 | 0.86 | IDO1 (0.58) | LMNATAAR1IDO1LOXL2CYP3A4 | |
| SCHEMBL13808352 | 0.84 | ACHE (0.68) | ACHENFE2L2LMNAKMT2AGAA | |
| Hydrochloric Acid SCHEMBL7941845 | 0.83 | IDO1 (0.55) | LMNATAAR1IDO1LOXL2CYP3A4 | |
| SCHEMBL12689 | 0.83 | — | — | |
| SCHEMBL7025938 | 0.83 | — | — | |
| Dimethylamine SCHEMBL23675374 | 0.80 | ACHE (0.81) | ACHENFE2L2LMNAKMT2AGAA | |
| SCHEMBL28577273 | 0.80 | ACHE (0.62) | ACHENFE2L2LMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943199-B | Method for synthesizing amide compound by using nitrile and diaryl methane as raw materials | 浙江工业大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-112851608-B | Catalytic oxidation synthesis method of 2-diaryl methyl benzofuran compound | 浙江工业大学 | 2022-07-15 | — | — | CN | disclosed |
| WO-2022125876-A1 | COMPOSITIONS AND METHODS FOR INHIBITING HAIR GROWTH | OLSEN ELISE A (US) | 2022-06-16 | — | — | WO | disclosed |
| CN-113943199-A | Method for synthesizing amide compound by taking nitrile and diarylmethane as raw materials | 浙江工业大学 | 2022-01-18 | — | — | CN | disclosed |
| WO-2021156636-A1 | TRIAZOLE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | KING'S COLLEGE LONDON (GB) | 2021-08-12 | — | — | WO | disclosed |
| CN-112851608-A | Catalytic oxidation synthesis method of 2-diaryl methyl benzofuran compound | 浙江工业大学 | 2021-05-28 | — | — | CN | disclosed |
| US-20180186754-A1 | SYNTHESES OF N-HETEROCYCLIC CARBENES AND INTERMEDIATES THEREFOR | UMICORE AG & CO. KG (DE) | 2018-07-05 | — | — | US | disclosed |
| US-9890125-B2 | Syntheses of N-heterocyclic carbenes and intermediates therefor | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2018-02-13 | — | — | US | disclosed |
| WO-2017213252-A1 | OXADIAZOLE COMPOUND AND USE AS PESTICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-12-14 | — | — | WO | disclosed |
| US-20170152231-A9 | SYNTHESES OF N-HETEROCYCLIC CARBENES AND INTERMEDIATES THEREFOR | UMICORE AG & CO. KG (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20090177014-A1 | Process for Preparing 4,4' Difluorobenzophenone | EVONIK FIBRES GMBH (AT) | 2009-07-09 | — | — | US | disclosed |
| EP-1910259-A1 | PROCESS FOR PREPARING 4,4'-DIFLUOROBENZOPHENONE | Evonik Fibres GmbH (AT) | 2008-04-16 | — | — | EP | disclosed |
| US-20070270422-A1 | Aromatic Compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| US-20070270422-A1 | Aromatic Compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| WO-2007066784-A2 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007014692-A1 | PROCESS FOR PREPARING 4,4'-DIFLUOROBENZOPHENONE | EVONIK FIBRES GMBH (AT) | 2007-02-08 | — | — | WO | disclosed |
| US-6951918-B2 | Peptidic procollagen C-proteinase inhibitors | SYNTEX (U.S.A.) LLC (US) | 2005-10-04 | — | — | US | disclosed |
| EP-1466605-A2 | Calcium channel blockers | Neuromed Technologies Inc. (CA) | 2004-10-13 | — | — | EP | disclosed |
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090177014-A1 | Process for Preparing 4,4' Difluorobenzophenone | FDPS, FGB, FOSB | ACHE 2217/4885NFE2L2 271/4885LMNA 4682/4885 |
| US-20170152231-A9 | SYNTHESES OF N-HETEROCYCLIC CARBENES AND INTERMEDIATES THEREFOR | GRHPR, DDC, WEE2 | ACHE 3125/4885NFE2L2 323/4885LMNA 3135/4885 |
| US-20180186754-A1 | SYNTHESES OF N-HETEROCYCLIC CARBENES AND INTERMEDIATES THEREFOR | GRHPR, DDC, NDC1 | ACHE 2977/4885NFE2L2 314/4885LMNA 3246/4885 |
| US-20070270422-A1 | Aromatic Compounds | COL1A1, COL2A1, COL14A1 | ACHE 2757/4885NFE2L2 888/4885LMNA 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.