Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13792046 | 0.84 | THRB (0.39) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 | |
| SCHEMBL9624302 | 0.78 | PDF (0.34) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 | |
| SCHEMBL7599923 | 0.77 | ALDH1A1 (0.56) | ALDH1A1CYP2C9CYP2C19L3MBTL1TAS1R3 | |
| SCHEMBL1866598 | 0.77 | TGFBR1 (0.48) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 | |
| SCHEMBL17093839 | 0.77 | CTSK (0.44) | CYP2C9CYP2C19CA1CA2 | |
| SCHEMBL937622 | 0.77 | CTSK (0.44) | CYP2C9CYP2C19CA1CA2 | |
| SCHEMBL2441956 | 0.77 | CTSK (0.44) | CYP2C9CYP2C19CA1CA2 | |
| SCHEMBL28981492 | 0.76 | L3MBTL1 (0.47) | ALDH1A1CYP2C9CYP2C19HSD17B10L3MBTL1 | |
| SCHEMBL634032 | 0.76 | FOLH1 (0.46) | FOLH1 | |
| SCHEMBL1762251 | 0.75 | THRB (0.47) | ALDH1A1CYP2C9THRBCYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068371-A2 | PREPARATION OF ALKENES BY MILD THERMOLYSIS OF SULFOXIDES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2010-06-17 | — | — | WO | disclosed |