Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 6/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31402282 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL2664139 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL274871 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL26705583 | 0.83 | TUBB1 (0.50) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL21558457 | 0.79 | LMNA (0.50) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL21558730 | 0.79 | ERN1 (0.47) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL15110816 | 0.78 | ERN1 (0.50) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL419596 | 0.78 | ALDH1A1 (0.57) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL172939 | 0.78 | ALDH1A1 (0.71) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL29392394 | 0.78 | ALDH1A1 (0.71) | ALDH1A1TSHRKDM4ETDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802558-B1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | CONSEJO NAC DE INVEST ES CIENTÍFICAS Y TÉCNICAS CONICET (AR) | 2016-06-01 | — | — | EP | claimed |
| US-9255071-B2 | Compounds having antibacterial activity, process for their preparation and pharmaceutical compositions comprising them | CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TÉCNICAS (CONICET) (AR) | 2016-02-09 | — | — | US | claimed |
| US-20140357678-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET) (AR) | 2014-12-04 | — | — | US | claimed |
| EP-2802558-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TÉCNICAS (CONICET) (AR) | 2014-11-19 | — | — | EP | claimed |
| WO-2013105053-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | CONSEJO NACIONAL DE INVESTIGACIONES CIENTÍFICAS Y TÉCNICAS (CONICET) (AR) | 2013-07-18 | — | — | WO | claimed |
| EP-3085688-B1 | ADAMANTANE OR PINENE DERIVATIVES FOR USE IN THE TREATMENT OF CHLAMYDIALES INFECTIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2020-08-19 | — | — | EP | disclosed |
| EP-3085688-B1 | ADAMANTANE OR PINENE DERIVATIVES FOR USE IN THE TREATMENT OF CHLAMYDIALES INFECTIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2020-08-19 | — | — | EP | disclosed |
| US-10039727-B2 | Adamantane or pinene derivatives for use in the treatment of chlamydiales infections | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2018-08-07 | — | — | US | disclosed |
| US-10039727-B2 | Adamantane or pinene derivatives for use in the treatment of chlamydiales infections | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2018-08-07 | — | — | US | disclosed |
| EP-2872490-B1 | ANTIPROLIFERATIVE BENZO[B]AZEPIN-2-ONES | HOFFMANN LA ROCHE (CH) | 2018-02-07 | — | — | EP | disclosed |
| US-9629822-B2 | Flavonoid based antiviral targets | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-9611224-B2 | Antiproliferative benzo [B] azepin-2-ones | HOFFMANN-LA ROCHE INC. (US) | 2017-04-04 | — | — | US | disclosed |
| US-6369074-B1 | Aminomethylene substituted non-aromatic heterocycles and use as substance P antagonists | PFIZER INC. | 2002-04-09 | — | — | US | disclosed |
| US-20010023248-A1 | Aminomethylene substituted non-aromatic heterocycles and use as substance P antagonists | HOWARD HARRY R (US) | 2001-09-20 | — | — | US | disclosed |
| EP-0675886-B1 | AMINOMETHYLENE SUBSTITUTED NON-AROMATIC HETEROCYCLES AND USE AS SUBSTANCE P ANTAGONISTS | PFIZER (US) | 2000-07-05 | — | — | EP | disclosed |
| US-5854262-A | Aminomethylene substituted non-aromatic heterocycles and use as substance P antagonists | PFIZER INC. (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0806423-A1 | Aminomethylene substituted non-aromatic heterocycles and use as substance p antagonists | PFIZER INC. (US) | 1997-11-12 | — | — | EP | disclosed |
| EP-0675886-A1 | AMINOMETHYLENE SUBSTITUTED NON-AROMATIC HETEROCYCLES AND USE AS SUBSTANCE P ANTAGONISTS | PFIZER INC. (US) | 1995-10-11 | — | — | EP | disclosed |
| CN-1092771-A | The non-aromatic heterocycles that aminomethylene replaces | PFIZER (US) | 1994-09-28 | — | — | CN | disclosed |
| WO-1994013663-A1 | AMINOMETHYLENE SUBSTITUTED NON-AROMATIC HETEROCYCLES AND USE AS SUBSTANCE P ANTAGONISTS | PFIZER INC. (US) | 1994-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010023248-A1 | Aminomethylene substituted non-aromatic heterocycles and use as substance P antagonists | NPY1R, OPRK1, OPRL1 | ALDH1A1 856/4885TSHR 1323/4885KDM4E 1271/4885 |
| US-10039727-B2 | Adamantane or pinene derivatives for use in the treatment of chlamydiales infections | ADRA1A, ADRA1B, ADRA1D | ALDH1A1 30/4885TSHR 4466/4885KDM4E 4873/4885 |
| US-20140357678-A1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | C5, CBR3, C1R | ALDH1A1 1871/4885TSHR 224/4885KDM4E 2424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.