SCHEMBL373929

SCHEMBL373929

Cn1cc(C(=O)Nc2ccccc2-c2cc(F)c(Cl)c(Cl)c2)c(C(F)(F)F)n1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
POLB P06746 2/20 0.53
NTRK1 P04629 5/20 0.46
WDR5 P61964 2/20 0.42
TRPV1 Q8NER1 1/20 0.42
MAPK1 P28482 1/20 0.41
STING1 Q86WV6 1/20 0.41
ATM Q13315 1/20 0.40
CHRM3 P20309 2/20 0.40
BACE1 P56817 2/20 0.40
BACE2 Q9Y5Z0 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL374213 0.95 LMNA (0.56) LMNAPOLBNTRK1WDR5TRPV1
SCHEMBL29688585 0.90 LMNA (0.52) LMNAPOLBNTRK1WDR5MAPK1
SCHEMBL303861 0.90 LMNA (0.52) LMNAPOLBNTRK1WDR5MAPK1
SCHEMBL386461 0.89 LMNA (0.51) LMNAPOLBNTRK1WDR5MAPK1
SCHEMBL2351992 0.88 LMNA (0.55) LMNAPOLBNTRK1TRPV1MAPK1
SCHEMBL302840 0.88 LMNA (0.60) LMNAPOLBNTRK1STING1ATM
SCHEMBL4791610 0.87 LMNA (0.54) LMNAPOLBNTRK1WDR5MAPK1
SCHEMBL302383 0.87 LMNA (0.53) LMNAPOLBNTRK1WDR5STING1
SCHEMBL4450835 0.86 LMNA (0.56) LMNAPOLBNTRK1WDR5STING1
SCHEMBL4443686 0.85 LMNA (0.53) LMNAPOLBNTRK1WDR5STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110177944-A1 Synergistic Fungicidal Mixtures BASF SE (DE) 2011-07-21 US claimed
EP-2306832-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2011-04-13 EP claimed
WO-2009147205-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2009-12-10 WO claimed
US-20250312289-A1 METHODS AND COMPOSITIONS COMPRISING TOBACCO MILD GREEN MOSAIC VIRUS (TMGMV) UNIV CALIFORNIA (US) 2025-10-09 US disclosed
EP-2991490-B1 APPLYING A PESTICIDE-COMPRISING DISPERSION OF AN ALIPHATIC POLYURETHANE TO PLANTS BASF SE (DE) 2020-10-14 EP disclosed
EP-3102032-B1 SEED COATING FORMULATIONS AND THEIR USE FOR YIELD INCREASE BASF CORP (US) 2019-04-10 EP disclosed
EP-2192837-B1 FUNGICIDAL MIXTURES OF TRITICONAZOLE AND DIFENOCONAZOLE BASF SE (DE) 2017-05-10 EP disclosed
EP-3102032-A1 Seed coating formulations and their use for yield increase BASF Corporation (US) 2016-12-14 EP disclosed
US-20160345575-A1 Seed Coating Formulations and Their Use for Yield Increase BASF CORPORATION (US) 2016-12-01 US disclosed
EP-2408298-B1 METHOD FOR TREATMENT OF CROP WITH AN ENCAPSULATED PESTICIDE BASF SE (DE) 2016-06-29 EP disclosed
US-20160100576-A1 APPLYING A PESTICIDE-COMPRISING DISPERSION OF AN ALIPHATIC POLYURETHANE TO PLANTS BASF SE (DE) 2016-04-14 US disclosed
WO-2009153231-A2 AGROCHEMICAL FORMULATION COMPRISING A PESTICIDE, AN ORGANIC UV PHOTOPROTECTIVE FILTER AND COATED METAL OXIDE NANOPARTICLES BASF SE (DE) 2009-12-23 WO disclosed
WO-2009147205-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2009-12-10 WO disclosed
WO-2009124920-A2 EMULSIFIABLE CONCENTRATE BASF SE (DE) 2009-10-15 WO disclosed
WO-2009071449-A1 PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS BASF SE (DE) 2009-06-11 WO disclosed
WO-2009071448-A1 PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS BASF SE (DE) 2009-06-11 WO disclosed
WO-2009065834-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2009-05-28 WO disclosed
WO-2009053250-A1 FUNGICIDAL COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF TO COMBAT DAMAGING FUNGI, AND AGENTS COMPRISING THE SAME BASF SE (DE) 2009-04-30 WO disclosed
WO-2009037162-A2 FUNGICIDAL MIXTURES OF TRITICONAZOLE AND DIFENOCONAZOLE BASF SE (DE) 2009-03-26 WO disclosed
WO-2009019176-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177944-A1 Synergistic Fungicidal Mixtures CYP3A5, CYP51A1, CYP3A7 LMNA 4642/4885POLB 3322/4885NTRK1 4813/4885
US-20160100576-A1 APPLYING A PESTICIDE-COMPRISING DISPERSION OF AN ALIPHATIC POLYURETHANE TO PLANTS DDT, DDC, DERL1 LMNA 2740/4885POLB 1581/4885NTRK1 4697/4885
US-20160345575-A1 Seed Coating Formulations and Their Use for Yield Increase CLTB, STUB1, CBLB LMNA 2176/4885POLB 1613/4885NTRK1 2960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.