Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719137 | 0.90 | MAPT (0.47) | MAOAMAOBRAB9ALMNANPC1 | |
| SCHEMBL2382432 | 0.89 | LMNA (0.69) | MAOAMAOBRAB9ALMNANPC1 | |
| SCHEMBL9455528 | 0.81 | MAOA (0.81) | MAOAMAOBRAB9ALMNANPC1 | |
| Xanthene SCHEMBL30586075 | 0.81 | MAOA (1.00) | MAOAMAOBRAB9ALMNANPC1 | |
| Xanthene SCHEMBL27493963 | 0.81 | MAOA (1.00) | MAOAMAOBRAB9ALMNANPC1 | |
| Xanthene SCHEMBL29378346 | 0.81 | MAOA (1.00) | MAOAMAOBRAB9ALMNANPC1 | |
| Xanthene SCHEMBL4267 | 0.81 | MAOA (1.00) | MAOAMAOBRAB9ALMNANPC1 | |
| Xanthene SCHEMBL9339684 | 0.81 | MAOA (1.00) | MAOAMAOBRAB9ALMNANPC1 | |
| SCHEMBL22044623 | 0.80 | MAOB (0.49) | MAOAMAOBRAB9ALMNANPC1 | |
| SCHEMBL9455608 | 0.79 | MAOA (0.77) | MAOAMAOBRAB9ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140363839-A1 | LONG WAVELENGTH FLUOROGENIC INTRACELLULAR ION INDICATORS THAT ARE WELL RETAINED IN THE CYTOSOL | Life Technologies Corporation (US) | 2014-12-11 | — | — | US | claimed |
| US-8318502-B2 | Long wavelength fluorogenic intracellular ion indicators that are well retained in the cytosol | Life Technologies Corporation (US) | 2012-11-27 | — | — | US | claimed |
| US-20100330584-A1 | LONG WAVELENGTH FLUOROGENIC INTRACELLULAR ION INDICATORS THAT ARE WELL RETAINED IN THE CYTOSOL | Life Technologies Corporation (US) | 2010-12-30 | — | — | US | claimed |
| WO-2008151303-A1 | LONG WAVELENGTH FLUOROGENIC INTERCELLULAR ION INDICATORS | INVITROGEN CORPORATION (US) | 2008-12-11 | — | — | WO | claimed |
| CN-116323965-A | Compositions, systems and methods for bioassays using dyes | 生命技术公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116075597-A | Energy transfer dye conjugates for use in bioassays | 生命技术公司 | 2023-05-05 | — | — | CN | disclosed |
| US-11453910-B2 | Controlling fluorescent signal composition in optically-based nanopore sequencing | QUANTAPORE, INC. (US) | 2022-09-27 | — | — | US | disclosed |
| CN-108463560-B | Optical-based nanopore analysis with reduced background | 昆塔波尔公司 | 2022-09-20 | — | — | CN | disclosed |
| US-20220170088-A1 | MIXED OPTICAL SIGNALS IN POLYMER ANALYSIS WITH NANOPORES | QUANTAPORE, INC. (US) | 2022-06-02 | — | — | US | disclosed |
| US-20220112551-A1 | OPTICALLY-BASED NANOPORE ANALYSIS WITH REDUCED BACKGROUND | QUANTAPORE, INC. (US) | 2022-04-14 | — | — | US | disclosed |
| EP-3482196-B1 | OPTICALLY BASED NANOPORE SEQUENCING | QUANTAPORE INC (US) | 2022-02-23 | — | — | EP | disclosed |
| US-20210285928-A1 | CONTROLLING FLUORESCENT SIGNAL COMPOSITION IN OPTICALLY-BASED NANOPORE SEQUENCING | QUANTAPORE, INC. (US) | 2021-09-16 | — | — | US | disclosed |
| US-20040229248-A1 | Novel dye labeling composition | ENZO LIFE SCIENCES, INC. | 2004-11-18 | — | — | US | disclosed |
| US-20040203038-A1 | Process for preparing novel cyanine dye labeling reagents | ENZO LIFE SCIENCES, INC. | 2004-10-14 | — | — | US | disclosed |
| US-20040192893-A1 | comprises cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes for use in labeling nucleic acids or proteins in assay, and as diagnostic aid in genomics/proteomics | ENZO LIFE SCIENCES, INC. (US) | 2004-09-30 | — | — | US | disclosed |
| US-20040176586-A1 | Process for detecting the presence or quantity of enzymatic activity in a sample | ENZO LIFE SCIENCES, INC. (US) | 2004-09-09 | — | — | US | disclosed |
| US-20030225247-A1 | Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses | ENZO LIFE SCIENCES, INC. | 2003-12-04 | — | — | US | disclosed |
| EP-1348713-A2 | Labeling reagents and labeled tabeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses | Enzo Life Sciences, Inc. (US) | 2003-10-01 | — | — | EP | disclosed |
| EP-1344835-A2 | Real-time nucleic acid detection processes and compositions | Enzo Life Sciences, Inc. (US) | 2003-09-17 | — | — | EP | disclosed |
| US-6323337-B1 | DETECTING AMPLIFICATION OF TARGET NUCLEIC ACID THAT REDUCES FLUORESCENCE; LUMINESCENCE REDUCTION; COVALENTLY BONDING | MOLECULAR PROBES, INC. | 2001-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100330584-A1 | LONG WAVELENGTH FLUOROGENIC INTRACELLULAR ION INDICATORS THAT ARE WELL RETAINED IN THE CYTOSOL | CHERP, MCU, GLB1 | MAOA 3219/4885MAOB 3253/4885RAB9A 1656/4885 |
| US-20040229248-A1 | Novel dye labeling composition | IK, PHAX, CHLSN | MAOA 3601/4885MAOB 3350/4885RAB9A 4349/4885 |
| US-20040203038-A1 | Process for preparing novel cyanine dye labeling reagents | PHAX, IK, CHLSN | MAOA 3292/4885MAOB 3066/4885RAB9A 4291/4885 |
| US-20040176586-A1 | Process for detecting the presence or quantity of enzymatic activity in a sample | RNGTT, POLRMT, CHLSN | MAOA 814/4885MAOB 891/4885RAB9A 4308/4885 |
| US-20030225247-A1 | Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses | POLRMT, CHLSN, PHAX | MAOA 3066/4885MAOB 2998/4885RAB9A 4273/4885 |
| US-20040192893-A1 | comprises cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes for use in labeling nucleic acids or proteins in assay, and as diagnostic aid in genomics/proteomics | CHLSN, DDB1, PROC | MAOA 3515/4885MAOB 3477/4885RAB9A 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.