Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374168 | 0.90 | MAOA (0.65) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL17819520 | 0.88 | AHR (0.47) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL28164465 | 0.81 | RAB9A (0.58) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL13296930 | 0.80 | ALDH1A1 (0.49) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL10824984 | 0.80 | MAPT (0.43) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL17827861 | 0.77 | NPC1 (0.40) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL17820428 | 0.77 | MAPT (0.41) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL17820037 | 0.77 | SMN1; SMN2 (0.40) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL22044622 | 0.77 | ALDH1A1 (0.47) | MAPTKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL2382432 | 0.77 | LMNA (0.69) | MAPTKDM4ELMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140363839-A1 | LONG WAVELENGTH FLUOROGENIC INTRACELLULAR ION INDICATORS THAT ARE WELL RETAINED IN THE CYTOSOL | Life Technologies Corporation (US) | 2014-12-11 | — | — | US | claimed |
| EP-2445969-B1 | NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES | MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) | 2014-08-27 | — | — | EP | claimed |
| US-8735444-B2 | Fluorinated rhodamines as photostable fluorescent dyes for labelling and imaging techniques | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2014-05-27 | — | — | US | claimed |
| US-8318502-B2 | Long wavelength fluorogenic intracellular ion indicators that are well retained in the cytosol | Life Technologies Corporation (US) | 2012-11-27 | — | — | US | claimed |
| US-20120135459-A1 | NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-05-31 | — | — | US | claimed |
| EP-2445969-A1 | NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2012-05-02 | — | — | EP | claimed |
| US-20100330584-A1 | LONG WAVELENGTH FLUOROGENIC INTRACELLULAR ION INDICATORS THAT ARE WELL RETAINED IN THE CYTOSOL | Life Technologies Corporation (US) | 2010-12-30 | — | — | US | claimed |
| WO-2010149190-A1 | NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES | MAX-PLANCK-GESELLSCHAFT ZUR (DE) | 2010-12-29 | — | — | WO | claimed |
| WO-2008151303-A1 | LONG WAVELENGTH FLUOROGENIC INTERCELLULAR ION INDICATORS | INVITROGEN CORPORATION (US) | 2008-12-11 | — | — | WO | claimed |
| JP-61165307-A | — | — | None | — | — | JP | disclosed |
| US-12140540-B2 | Stimulated Raman coupled fluorescence spectroscopy and microscopy system and method | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-11-12 | — | — | US | disclosed |
| US-20240201189-A1 | FLUORESCENT PROBE FOR USE IN DETECTION OF PANCREATIC CANCER | THE UNIVERSITY OF TOKYO (JP) | 2024-06-20 | — | — | US | disclosed |
| US-20220341922-A1 | FLUORESCENT PROBE FOR USE IN DETECTION OF BRAIN TUMOR | THE UNIVERSITY OF TOKYO (JP) | 2022-10-27 | — | — | US | disclosed |
| WO-2022220232-A1 | FLUORESCENT PROBE FOR USE IN DETECTION OF PANCREATIC CANCER | 国立大学法人 東京大学 | 2022-10-20 | — | — | WO | disclosed |
| US-5686261-A | FLUORESCENT DYES FOR STAINING MITOCHONDRIA | MOLECULAR PROBES, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5459268-A | Fluorescent dyes | MOLECULAR PROBES, INC. (US) | 1995-10-17 | — | — | US | disclosed |
| US-5459268-A | Fluorescent dyes | MOLECULAR PROBES, INC. (US) | 1995-10-17 | — | — | US | disclosed |
| US-5331097-A | Improved solubility and fugitivity, dyeing carpet | MILLIKEN RESEARCH CORPORATION (US) | 1994-07-19 | — | — | US | disclosed |
| EP-0527649-A2 | Poly(oxyalkylene) substituted xanthene colorant and method for making the same | MILLIKEN RESEARCH CORPORATION (US) | 1993-02-17 | — | — | EP | disclosed |
| JP-S61165307-A | HERBICIDE CONTAINING 3,6-DIAMINOXANTHENE DERIVATIVE | ASAHI CHEM IND CO LTD | 1986-07-26 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100330584-A1 | LONG WAVELENGTH FLUOROGENIC INTRACELLULAR ION INDICATORS THAT ARE WELL RETAINED IN THE CYTOSOL | CHERP, MCU, GLB1 | MAPT 3427/4885KDM4E 4134/4885LMNA 205/4885 |
| US-20220341922-A1 | FLUORESCENT PROBE FOR USE IN DETECTION OF BRAIN TUMOR | GLRA1, PNISR, ARGLU1 | MAPT 4162/4885KDM4E 4055/4885LMNA 4297/4885 |
| US-20240201189-A1 | FLUORESCENT PROBE FOR USE IN DETECTION OF PANCREATIC CANCER | RNASE1, SLC67A1, AMY2A | MAPT 4675/4885KDM4E 4859/4885LMNA 3324/4885 |
| US-20120135459-A1 | NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES | SNRPD1, SRSF6, DRD1 | MAPT 724/4885KDM4E 2730/4885LMNA 1001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.