Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | DBH | P09172 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256220 | 0.87 | ACHE (0.46) | ACHEMAPTHPGDL3MBTL1MAPK1 | |
| SCHEMBL10196055 | 0.85 | ACHE (0.70) | ACHEMAPTHPGDL3MBTL1MAPK1 | |
| SCHEMBL12216295 | 0.84 | ACHE (0.43) | ACHEMAPTHPGDL3MBTL1MAPK1 | |
| SCHEMBL442742 | 0.81 | ALDH1A1 (0.44) | MAPTHPGDL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL54507 | 0.80 | KMT2A (0.47) | MAPTHPGDL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL12325399 | 0.80 | ALDH1A1 (0.47) | ACHEHPGDL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8430640 | 0.78 | ALDH1A1 (0.53) | HPGDALDH1A1KDM4EGAATAS1R3 | |
| SCHEMBL14417407 | 0.78 | ALDH1A1 (0.41) | ACHEMAPTHPGDL3MBTL1MAPK1 | |
| SCHEMBL1387190 | 0.76 | ALDH1A1 (0.44) | ACHEHPGDL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL17110036 | 0.76 | ALDH1A1 (0.44) | ACHEHPGDL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273139-A1 | 2-PYRIDONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | KPC Pharmaceuticals, Inc. (CN) | 2023-11-08 | — | — | EP | disclosed |
| US-11664093-B2 | Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-30 | — | — | US | disclosed |
| US-20210147351-A9 | ANTIFUNGAL COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| US-20200140381-A1 | ANTIFUNGAL COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-05-07 | — | — | US | disclosed |
| EP-2916840-B1 | SUBSTITUTED GEMCITABINE ARYL AMIDE ANALOGS | NUCORION PHARMACEUTICALS INC (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9744186-B2 | Substituted gemcitabine aryl amide analogs | NUCORION PHARMACEUTICALS, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| WO-2017143230-A1 | ANTIFUNGAL COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-08-24 | — | — | WO | disclosed |
| US-20170204110-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | FLATLEY DISCOVERY LAB, LLC | 2017-07-20 | — | — | US | disclosed |
| US-20160354399-A1 | SUBSTITUTED GEMCITABINE ARYL AMIDE ANALOGS | THE OHIO STATE UNIVERSITY | 2016-12-08 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-20080113994-A1 | Annelated Quinoline Derivatives As Pesticide | VELTEN ROBERT | 2008-05-15 | — | — | US | disclosed |
| US-20080076792-A1 | Heterobifunctional Polymeric Bioconjugates | ENZON PHARMACEUTICALS, INC. (US) | 2008-03-27 | — | — | US | disclosed |
| US-20080064871-A1 | Production Method of Nitrogen-Containing Fused Ring Compounds | JAPAN TOBACCO INC. (JP) | 2008-03-13 | — | — | US | disclosed |
| US-7169785-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| EP-1080069-B1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-20020193614-A1 | Anthranilic acid derivatives as inhibitors of the CGMP-phosphodiesterase | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-12-19 | — | — | US | disclosed |
| US-6384080-B1 | TREATMENT AND/OR PREVENTION OF CERTAIN CARDIOVASCULAR DISORDERS, UROGENITAL DISORDERS, RESPIRATORY SYSTEM DISORDERS, DISORDERS OF GUT MOTILITY, SEXUAL DISORDERS, DIABETIC COMPLICATIONS, URTICARIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| CN-1305454-A | Anthranilic acid derivatives as inhibitors of CGMP phosphodiesterase | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-07-25 | — | — | CN | disclosed |
| EP-1080069-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999054284-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147351-A9 | ANTIFUNGAL COMPOUNDS AND USES THEREOF | ERG28, DPM1, CYP51A1 | ACHE 2706/4885MAPT 950/4885HPGD 1479/4885 |
| US-20020193614-A1 | Anthranilic acid derivatives as inhibitors of the CGMP-phosphodiesterase | PDE3A, PDE2A, PDE5A | ACHE 185/4885MAPT 4706/4885HPGD 76/4885 |
| US-20080113994-A1 | Annelated Quinoline Derivatives As Pesticide | DDT, ACHE, SIRT4 | ACHE 2/4885MAPT 2367/4885HPGD 3073/4885 |
| US-20080076792-A1 | Heterobifunctional Polymeric Bioconjugates | PAICS, FCGR3B, FCGR2A | ACHE 1085/4885MAPT 2550/4885HPGD 1751/4885 |
| US-20200140381-A1 | ANTIFUNGAL COMPOUNDS AND USES THEREOF | ERG28, DPM1, CYP51A1 | ACHE 2706/4885MAPT 950/4885HPGD 1479/4885 |
| US-20170204110-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, SERPINB1, ELANE | ACHE 3588/4885MAPT 4860/4885HPGD 379/4885 |
| US-20160354399-A1 | SUBSTITUTED GEMCITABINE ARYL AMIDE ANALOGS | KRAS, NRAS, GMNN | ACHE 3445/4885MAPT 3845/4885HPGD 3799/4885 |
| US-20080064871-A1 | Production Method of Nitrogen-Containing Fused Ring Compounds | NOD1, XDH, URB2 | ACHE 3906/4885MAPT 1019/4885HPGD 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.