SCHEMBL3755778

SCHEMBL3755778

O=C(C(=O)c1ccc(N(c2ccccc2)c2ccccc2)cc1)c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 12/20 0.64
CES1 P23141 11/20 0.64
RAB9A P51151 2/20 0.63
ALDH1A1 P00352 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
NPC1 O15118 1/20 0.47
HPGD P15428 1/20 0.47
MEN1 O00255 1/20 0.47
CRHBP P24387 1/20 0.47
KMT2A Q03164 1/20 0.47
ATM Q13315 1/20 0.47
CRHR2 Q13324 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14982120 0.98 CES2 (0.68) CES2CES1RAB9AALDH1A1L3MBTL1
SCHEMBL20287990 0.94 RAB9A (0.57) CES2CES1RAB9AALDH1A1L3MBTL1
SCHEMBL28105405 0.90 ALDH1A1 (0.69) CES2CES1RAB9AALDH1A1L3MBTL1
SCHEMBL329666 0.86 RAB9A (0.63) RAB9AALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL2596293 0.86 TSHR (0.59) CES2CES1RAB9AALDH1A1L3MBTL1
SCHEMBL1246652 0.86 TSHR (0.59) CES2CES1RAB9AALDH1A1L3MBTL1
SCHEMBL1246651 0.84 ALDH1A1 (0.48) CES2CES1RAB9AALDH1A1L3MBTL1
SCHEMBL329499 0.84 RAB9A (0.67) CES2CES1RAB9AALDH1A1L3MBTL1
SCHEMBL8684872 0.84 RAB9A (0.67) CES2CES1RAB9AALDH1A1L3MBTL1
Terephthalic Acid SCHEMBL10615446 0.83 TSHR (0.62) CES2CES1ALDH1A1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217500-B Cyano quinoxaline red light thermal excitation delayed fluorescent material, synthetic method and application thereof 黑龙江大学 2025-05-16 CN disclosed
US-12162889-B2 Luminogens for biological applications THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-12-10 US disclosed
CN-110312708-B Luminescent materials for biological applications 香港科技大学 2023-07-18 CN disclosed
CN-116217500-A Cyano quinoxaline red light thermal excitation delayed fluorescent material, synthetic method and application thereof 黑龙江大学 2023-06-06 CN disclosed
CN-113200929-B Cyano quinoxaline red light thermal excitation delayed fluorescent material, synthetic method and application thereof 黑龙江大学 2023-04-28 CN disclosed
CN-114709329-A Nano nerve morphological device with organic two-dimensional conjugated symmetry polymer as active layer and preparation method and application thereof 华东理工大学 2022-07-05 CN disclosed
CN-111834524-B Conjugated polymer memory device with nonvolatile memory rewritable property and preparation method and application thereof 华东理工大学 2022-04-26 CN disclosed
US-20220048923-A1 LUMINOGENS FOR BIOLOGICAL APPLICATIONS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2022-02-17 US disclosed
US-20220048923-A1 LUMINOGENS FOR BIOLOGICAL APPLICATIONS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2022-02-17 US disclosed
US-11186586-B2 Luminogens for biological applications THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2021-11-30 US disclosed
US-11186586-B2 Luminogens for biological applications THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2021-11-30 US disclosed
US-20200079787-A1 LUMINOGENS FOR BIOLOGICAL APPLICATIONS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2020-03-12 US disclosed
US-7842830-B2 Transition-metal charge-transport materials, methods of fabrication thereof, and methods of use thereof GEORGIA TECH RESEARCH CORPORATION (US) 2010-11-30 US disclosed
US-20080121870-A1 Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof GEORGIA TECH RESEACH CORPORATION 2008-05-29 US disclosed
WO-2005123754-A2 TRANSITION-METAL CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2005-12-29 WO disclosed
US-6617053-B2 High luminous efficiency and a long life CHISSO CORPORATION (JP) 2003-09-09 US disclosed
US-20020027415-A1 Organic electroluminescent device containing dithiafulvene derivative CHISSO CORPORATION (JP) 2002-03-07 US disclosed
US-4349617-A Function separated type electrophotographic light-sensitive members and process for production thereof FUJI PHOTO FILM CO., LTD. (JP) 1982-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162889-B2 Luminogens for biological applications BTD, TPD52L2, TTPA CES2 2500/4885CES1 3416/4885RAB9A 3980/4885
US-20200079787-A1 LUMINOGENS FOR BIOLOGICAL APPLICATIONS BTD, LTA, TPD52L2 CES2 2973/4885CES1 3628/4885RAB9A 3823/4885
US-20220048923-A1 LUMINOGENS FOR BIOLOGICAL APPLICATIONS BTD, TPD52L2, TTPA CES2 2500/4885CES1 3416/4885RAB9A 3980/4885
US-20080121870-A1 Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof SLC39A3, SLC6A6, SLC6A9 CES2 1387/4885CES1 4295/4885RAB9A 521/4885
US-11186586-B2 Luminogens for biological applications BTD, LTA, TPD52L2 CES2 2973/4885CES1 3628/4885RAB9A 3823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.