SCHEMBL377789

SCHEMBL377789

O=Cc1cccc(OCCO)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.58
MAOB P27338 7/20 0.58
SRC P12931 1/20 0.53
NPC1 O15118 4/20 0.53
RAB9A P51151 4/20 0.53
TDP1 Q9NUW8 1/20 0.53
ALDH1A1 P00352 2/20 0.52
RECQL P46063 1/20 0.52
FURIN P09958 1/20 0.45
TLR4 O00206 1/20 0.43
TLR2 O60603 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 1/20 0.43
KMT2A Q03164 2/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
MEN1 O00255 1/20 0.42
S1PR1 P21453 1/20 0.42
S1PR3 Q99500 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29898196 1.00 MAOA (0.58) MAOAMAOBSRCNPC1RAB9A
SCHEMBL1036930 0.91 MAOA (0.57) MAOAMAOBSRCNPC1RAB9A
SCHEMBL29096214 0.90 MAOA (0.53) MAOAMAOBSRCNPC1RAB9A
SCHEMBL15627380 0.90 MAOA (0.53) MAOAMAOBSRCNPC1RAB9A
SCHEMBL12595199 0.90 MAOA (0.55) MAOAMAOBSRCNPC1RAB9A
SCHEMBL5543437 0.89 MAOA (0.66) MAOAMAOBSRCNPC1RAB9A
SCHEMBL27717489 0.88 MAOA (0.54) MAOAMAOBSRCNPC1RAB9A
SCHEMBL27816601 0.88 MAOA (0.54) MAOAMAOBSRCNPC1RAB9A
SCHEMBL5361828 0.88 ALDH1A1 (0.54) MAOAMAOBSRCNPC1RAB9A
SCHEMBL30724528 0.87 MAOA (0.64) MAOAMAOBSRCNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160752-B Polylactic acid composite material for mulching film and application thereof 山西生物质新材料产业研究院有限公司 2023-08-01 CN claimed
CN-115160752-A Polylactic acid composite material for mulching film and application thereof 山西生物质新材料产业研究院有限公司 2022-10-11 CN claimed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
US-6635090-B1 Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL, S.A. (FR) 2003-10-21 US claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
JP-54106446-A None JP disclosed
EP-4731691-A1 CURABLE COMPOSITION HAVING AN ALDEHYDE-FUNCTIONAL POLYMER Sika Technology AG (CH) 2026-04-29 EP disclosed
US-20260070901-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTPR LTD (GB) 2026-03-12 US disclosed
EP-4695236-A1 SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE Soley Therapeutics, Inc. (US) 2026-02-18 EP disclosed
US-20250170283-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-29 US disclosed
US-20250034143-A1 SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF HYDRA BIOSCIENCES, LLC (US) 2025-01-30 US disclosed
EP-0541634-A1 1,4-DIHYDROPYRIDINE DERIVATIVES CEDONA PHARMACEUTICALS B.V. (NL) 1993-05-19 EP disclosed
EP-0530962-A1 Anti-blocking, water soluble top coat for color proofing films MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-03-10 EP disclosed
EP-0529896-A1 Light-sensitive article containing migration-resistant halomethyl-1,3,5-triazine photoinitiator MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-03-03 EP disclosed
EP-0529789-A1 Negative single sheet color proofing system based on aqueous developable photo-oligomers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-03-03 EP disclosed
WO-1992002503-A1 NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES CEDONA PHARMACEUTICALS BV (NL) 1992-02-20 WO disclosed
JP-S54106446-A SUBSTITUTED ALPHA-AMINOPHENYLACETIC ACID CHUGAI PHARMACEUT CO LTD 1979-08-21 JP disclosed
US-4053415-A UNSATURATED POLYESTER ETHER HAVING A PHOTOCROSSLINKABLE MOIETY FUJI PHOTO FILM CO., LTD. (JA) 1977-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170283-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 MAOA 258/4885MAOB 359/4885SRC 1705/4885
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 MAOA 467/4885MAOB 514/4885SRC 4663/4885
US-20250034143-A1 SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF TRPC5, TRPC7, TRPC4 MAOA 886/4885MAOB 518/4885SRC 4209/4885
US-20260070901-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CSNK1A1, CSNK2A3, CSNK1G1 MAOA 4502/4885MAOB 4075/4885SRC 1773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.