Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE known ✓ | P12821 | 1/20 | 0.40 |
| ▸ | CA4 known ✓ | P22748 | 4/20 | 0.35 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.35 |
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.35 |
| ▸ | SCN1A known ✓ | P35498 | 1/20 | 0.30 |
| ▸ | SCN2A known ✓ | Q99250 | 1/20 | 0.30 |
| ▸ | SCN3A known ✓ | Q9NY46 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10767426 | 0.98 | KDM4E (0.95) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| Water SCHEMBL9900448 | 0.98 | KDM4E (0.95) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL31349875 | 0.98 | KDM4E (0.95) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| Potassium Ion SCHEMBL2322535 | 0.95 | ALOX15 (0.91) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL9449227 | 0.95 | ALOX15 (0.91) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| Bicine SCHEMBL783494 | 0.95 | KDM4E (0.91) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL382697 | 0.95 | ALOX15 (0.91) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| Water SCHEMBL11884555 | 0.93 | ALOX15 (0.86) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL11339918 | 0.92 | KDM4E (0.84) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL31491190 | 0.92 | KDM4E (0.84) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4741492-A2 | NECROSIS INHIBITOR | Linkgevity Limited (GB) | 2026-05-13 | — | — | EP | claimed |
| EP-4648769-A2 | NECROSIS INHIBITOR | Linkgevity Limited (GB) | 2025-11-19 | — | — | EP | claimed |
| WO-2025050032-A1 | METHODS OF PRODUCING CDKL5 PROTEINS AND USES OF THE SAME | ULTRAGENYX PHARMACEUTICAL INC. (US) | 2025-03-06 | — | — | WO | claimed |
| WO-2024212088-A1 | HYDROGEN SYNTHESIS FROM HYDROGEN SULFIDE GAS | SAUDI ARABIAN OIL COMPANY (SA) | 2024-10-17 | — | — | WO | claimed |
| WO-2024152094-A1 | METHOD FOR REDUCING THE COLOURING OF SUGAR, PROCESS FOR PRODUCING SUGAR WITH LOW COLOUR, COMPOSITION AND USE OF A CHELATING AGENT | ITALMATCH CHEMICALS SPA (IT) | 2024-07-25 | — | — | WO | claimed |
| WO-2024150130-A2 | NECROSIS INHIBITOR | LINKGEVITY LIMITED (GB) | 2024-07-18 | — | — | WO | claimed |
| CN-116512716-A | Full-degradable heat-insulating film and preparation method and application thereof | 四川省交通建设集团有限责任公司 | 2023-08-01 | — | — | CN | claimed |
| US-11084971-B2 | Acidizing treatment fluids for use in subterranean formation operations | HALLIBURTON ENERGY SERVICES, INC. (US) | 2021-08-10 | — | — | US | claimed |
| EP-3263145-B1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | BECTON DICKINSON CO (US) | 2021-01-20 | — | — | EP | claimed |
| CN-111278787-A | Method for inhibiting gypsum seed formation in ready-mix setting type joint compounds | 美国石膏公司 | 2020-06-12 | — | — | CN | claimed |
| US-20070202177-A1 | Antimicrobial Compositions and Methods for Locking Catheters | BECTON, DICKINSON AND COMPANY (US) | 2007-08-30 | — | — | US | claimed |
| US-6890550-B1 | Method of preventing parturient hypocalcemia in animals and compositions used therein | RJ INNOVATION (DK) | 2005-05-10 | — | — | US | claimed |
| US-6670508-B2 | Quaternizing 1,3-bis-dimethylamineisopropyl acrylate with benzyl chloride at a temperature of 35-60 degrees C., adding water | ATOFINA (FR) | 2003-12-30 | — | — | US | claimed |
| EP-1245247-A1 | Biocidal locks | Biolink Corporation (US) | 2002-10-02 | — | — | EP | claimed |
| US-6350251-B1 | Biocidal locks | BIOLINK CORPORATION | 2002-02-26 | — | — | US | claimed |
| US-5447602-A | Adding to slurry, peroxide compound/s and non-alkali/alkaline earth metal salt or chelate catalyst to oxidize resin | HENKEL CORPORATION (US) | 1995-09-05 | — | — | US | claimed |
| EP-0145506-B1 | ELIMINATION OF DEFECTS IN CYSTEINE-SENSITIZED EMULSIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-03-02 | — | — | EP | claimed |
| US-4714804-A | Rotary switch having rotary contacts with an amorphous alloy coating | AISIN SEIKI KABUSHIKIKAISHA (JP) | 1987-12-22 | — | — | US | claimed |
| US-4558145-A | Preparation of Fe chelates | CIBA GEIGY CORPORATION (US) | 1985-12-10 | — | — | US | claimed |
| EP-0145506-A2 | Elimination of defects in cysteine-sensitized emulsions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-19 | — | — | EP | claimed |