SCHEMBL3800527

SCHEMBL3800527

O=C(O)CC=C(Cl)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
CYP2D6 P10635 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10703777 0.79
SCHEMBL8469715 0.77
SCHEMBL1936734 0.72
SCHEMBL465939 0.72
SCHEMBL6537398 0.72
SCHEMBL17188621 0.72
SCHEMBL18536 0.72
SCHEMBL1936731 0.72
SCHEMBL11218749 0.71 ALDH1A1 (0.47) ALDH1A1CYP2D6ALOX15TSHR
SCHEMBL13739882 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160158261-A1 Antibiotic Kit and Composition and Uses Thereof FOAMIX LTD. (IL) 2016-06-09 US claimed
US-9211259-B2 Antibiotic kit and composition and uses thereof FOAMIX PHARMACEUTICALS LTD. (IL) 2015-12-15 US claimed
EP-1919449-A2 ANTIBIOTIC KIT AND COMPOSITION AND USES THEREOF Foamix Ltd. (IL) 2008-05-14 EP claimed
WO-2007099396-A2 ANTIBIOTIC KIT AND COMPOSITION AND USES THEREOF FOAMIX LTD. (US) 2007-09-07 WO claimed
US-20060269485-A1 Antibiotic kit and composition and uses thereof FOAMIX LTD. (IL) 2006-11-30 US claimed
EP-4674476-A1 MAGNETIC FIELD VARIATION THERAPY FOR ENHANCING THERAPEUTIC AND DISINFECTION APPLICATIONS Azyro SA (LU) 2026-01-07 EP disclosed
EP-3802850-B1 DEVICES AND SYSTEMS FOR GASTROINTESTINAL MICROBIOME DETECTION AND MANIPULATION BT BIDCO INC (US) 2025-11-19 EP disclosed
US-20250082265-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOSUPPRESSANT BT BIDCO, INC. 2025-03-13 US disclosed
US-20250000364-A1 GASTROINTESTINAL TRACT DETECTION METHODS, DEVICES AND SYSTEMS GLAS USA LLC 2025-01-02 US disclosed
US-12150775-B2 Treatment of a disease of the gastrointestinal tract with an immunosuppressant BIORA THERAPEUTICS, INC. (US) 2024-11-26 US disclosed
CN-118873822-A Treatment of gastrointestinal disorders with TNF inhibitors 比奥拉治疗股份有限公司 2024-11-01 CN disclosed
US-20240335644-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNE MODULATORY AGENT RELEASED USING AN INGESTIBLE DEVICE GLAS USA LLC 2024-10-10 US disclosed
US-20080206161-A1 QUIESCENT FOAMABLE COMPOSITIONS, STEROIDS, KITS AND USES THEREOF FOAMIX PHARMACEUTICALS LTD. (IL) 2008-08-28 US disclosed
WO-2008075207-A2 ANTI-INFECTION AUGMENTATION FOAMABLE COMPOSITIONS AND KIT AND USES THEREOF FOAMIX LTD. (US) 2008-06-26 WO disclosed
EP-1919449-A2 ANTIBIOTIC KIT AND COMPOSITION AND USES THEREOF Foamix Ltd. (IL) 2008-05-14 EP disclosed
US-20080063607-A1 Oleaginous pharmaceutical and cosmetic foam FOAMIX LTD 2008-03-13 US disclosed
US-20070292461-A1 Oleaginous pharmaceutical and cosmetic foam FOAMIX LTD. (IL) 2007-12-20 US disclosed
US-20070292355-A1 Anti-infection augmentation foamable compositions and kit and uses thereof FOAMIX LTD. 2007-12-20 US disclosed
WO-2007099396-A2 ANTIBIOTIC KIT AND COMPOSITION AND USES THEREOF FOAMIX LTD. (US) 2007-09-07 WO disclosed
US-20060269485-A1 Antibiotic kit and composition and uses thereof FOAMIX LTD. (IL) 2006-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080206161-A1 QUIESCENT FOAMABLE COMPOSITIONS, STEROIDS, KITS AND USES THEREOF NR5A1, CYP17A1, LIPA ALDH1A1 1705/4885CYP2D6 3081/4885ALOX15 232/4885
US-20070292461-A1 Oleaginous pharmaceutical and cosmetic foam LIPA, LIPC, PLIN3 ALDH1A1 2577/4885CYP2D6 2614/4885ALOX15 76/4885
US-20070292355-A1 Anti-infection augmentation foamable compositions and kit and uses thereof CUTA, KIT, PRF1 ALDH1A1 2540/4885CYP2D6 4376/4885ALOX15 1998/4885
US-20250082265-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOSUPPRESSANT TPMT, FABP2, SLC10A2 ALDH1A1 2956/4885CYP2D6 732/4885ALOX15 307/4885
US-20240335644-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNE MODULATORY AGENT RELEASED USING AN INGESTIBLE DEVICE CD40LG, CD40, ICOS ALDH1A1 3879/4885CYP2D6 2638/4885ALOX15 154/4885
US-20250000364-A1 GASTROINTESTINAL TRACT DETECTION METHODS, DEVICES AND SYSTEMS FABP2, SI, MLNR ALDH1A1 2760/4885CYP2D6 288/4885ALOX15 2672/4885
US-20080063607-A1 Oleaginous pharmaceutical and cosmetic foam LIPA, LIPC, PLIN3 ALDH1A1 2577/4885CYP2D6 2614/4885ALOX15 76/4885
US-12150775-B2 Treatment of a disease of the gastrointestinal tract with an immunosuppressant TPMT, FABP2, SLC10A2 ALDH1A1 2956/4885CYP2D6 732/4885ALOX15 307/4885
US-20160158261-A1 Antibiotic Kit and Composition and Uses Thereof KIT, RAB5IF, CUTA ALDH1A1 1257/4885CYP2D6 2736/4885ALOX15 3394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.