Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521688 | 0.79 | APLNR (0.31) | LMNAKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL38239 | 0.76 | OXTR (0.35) | KDM4ENPC1RAB9A | |
| SCHEMBL715745 | 0.76 | RAB9A (0.44) | MAPTMAOBNPC1RAB9AHPGD | |
| SCHEMBL1456221 | 0.73 | NNMT (0.46) | LMNAKDM4EMAPTMAOBNNMT | |
| SCHEMBL38536 | 0.72 | CYP2A6 (0.49) | LMNANPC1MEN1KMT2A | |
| SCHEMBL14964686 | 0.72 | LMNA (0.34) | LMNAKDM4EMAPTMAOBNNMT | |
| SCHEMBL1752864 | 0.71 | LMNA (0.58) | LMNAKDM4EMAPTNPC1RAB9A | |
| SCHEMBL13052047 | 0.69 | ALDH1A1 (0.42) | LMNAKDM4EMAPTMAOBNNMT | |
| SCHEMBL353814 | 0.68 | NNMT (0.54) | LMNAKDM4EMAPTNNMTNPC1 | |
| SCHEMBL29795195 | 0.68 | NNMT (0.54) | LMNAKDM4EMAPTNNMTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |