Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157610 | 0.90 | NPC1 (0.33) | RAB9ANPC1L3MBTL1 | |
| SCHEMBL2158358 | 0.88 | POLB (0.39) | RAB9ANPC1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL3814650 | 0.78 | ACLY (0.39) | S1PR1LMNA | |
| SCHEMBL3809008 | 0.70 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL2158270 | 0.68 | PTPN22 (0.38) | — | |
| SCHEMBL2158355 | 0.68 | CCR2 (0.36) | ALDH1A1LMNA | |
| SCHEMBL3807904 | 0.68 | HSD17B1 (0.48) | ALDH1A1S1PR1LMNA | |
| SCHEMBL2158554 | 0.67 | — | — | |
| SCHEMBL3811057 | 0.66 | ALDH1A1 (0.48) | RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13270767 | 0.65 | LMNA (0.39) | S1PR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |