Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125897 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNABPTFEPHX2 | |
| SCHEMBL28056616 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNABPTFKMT2A | |
| SCHEMBL14973422 | 0.76 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2LMNABPTFEPHX2 | |
| SCHEMBL6536554 | 0.73 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNABPTFEPHX2 | |
| SCHEMBL704030 | 0.72 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2BPTFEPHX2MEN1 | |
| SCHEMBL2434575 | 0.72 | HSD11B1 (0.44) | P2RX7HSD11B1 | |
| SCHEMBL38655452 | 0.71 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNABPTFKMT2A | |
| SCHEMBL14644921 | 0.70 | LMNA (0.60) | ALDH1A1LMNABPTFP2RX7MAPT | |
| SCHEMBL17845447 | 0.70 | GAA (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL26114393 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601480-B2 | Photoactive compounds | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2009-10-13 | — | — | US | disclosed |
| EP-2102184-A2 | PHOTOACTIVE COMPOUNDS | AZ Electronic Materials USA Corp. (US) | 2009-09-23 | — | — | EP | disclosed |
| EP-2102156-A2 | PHOTOACTIVE COMPOUNDS | AZ Electronic Materials USA Corp. (US) | 2009-09-23 | — | — | EP | disclosed |
| US-7491482-B2 | Photoactive compounds | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2009-02-17 | — | — | US | disclosed |
| US-20080153032-A1 | Photoactive Compounds | MERCK PATENT GMBH (DE) | 2008-06-26 | — | — | US | disclosed |
| US-7390613-B1 | Photoactive compounds | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2008-06-24 | — | — | US | disclosed |
| WO-2008068617-A2 | PHOTOACTIVE COMPOUNDS | AZ ELECTRONIC MATERIALS USA CORP. (DE) | 2008-06-12 | — | — | WO | disclosed |
| WO-2008068610-A2 | PHOTOACTIVE COMPOUNDS | AZ ELECTRONIC MATERIALS USA CORP. (DE) | 2008-06-12 | — | — | WO | disclosed |
| US-20080131811-A1 | Photoactive Compounds | MERCK PATENT GMBH (DE) | 2008-06-05 | — | — | US | disclosed |
| US-20080131810-A1 | Photoactive Compounds | MERCK PATENT GMBH (DE) | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080131811-A1 | Photoactive Compounds | PRXL2A, PRDX2, AOC2 | ALDH1A1 1613/4885SMN1; SMN2 4288/4885LMNA 1844/4885 |
| US-20080131810-A1 | Photoactive Compounds | CRY2, AOC2, AFF2 | ALDH1A1 2000/4885SMN1; SMN2 3834/4885LMNA 1568/4885 |
| US-20080153032-A1 | Photoactive Compounds | SUN2, CRY2, SCO2 | ALDH1A1 3915/4885SMN1; SMN2 2213/4885LMNA 3487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.