Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18304700 | 0.83 | CES1 (0.37) | CES1PTPRC | |
| SCHEMBL384425 | 0.71 | CES1 (0.37) | CES1PTPRC | |
| SCHEMBL17837293 | 0.65 | — | — | |
| SCHEMBL38440 | 0.64 | — | — | |
| SCHEMBL2423612 | 0.62 | CDC7 (0.33) | CES1 | |
| SCHEMBL169947 | 0.61 | CES1 (0.35) | CES1PTPRC | |
| SCHEMBL332780 | 0.61 | GSK3B (0.37) | CES1PTPRC | |
| SCHEMBL336074 | 0.60 | — | — | |
| SCHEMBL2202905 | 0.58 | CES1 (0.52) | CES1PTPRC | |
| SCHEMBL209366 | 0.56 | S100A4 (0.42) | CES1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620813-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF AND ANGIOTENSIN II | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-10-26 | — | — | EP | claimed |
| WO-1993014069-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF AND ANGIOTENSIN II | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-07-22 | — | — | WO | claimed |
| US-20240228499-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2024-07-11 | — | — | US | disclosed |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
| US-20240207423-A1 | PROGAMMABLE POLYMERIC DRUGS | SONY GROUP CORP (JP) | 2024-06-27 | — | — | US | disclosed |
| US-20240210408-A1 | USE OF DIVALENT METALS FOR ENHANCEMENT OF FLUORESCENT SIGNALS | SONY GROUP CORP (JP) | 2024-06-27 | — | — | US | disclosed |
| US-12018159-B2 | Ultra bright dimeric or polymeric dyes and methods for preparation of the same | Sony Group Corporation (JP) | 2024-06-25 | — | — | US | disclosed |
| US-12006438-B2 | Polymeric dyes with linker groups comprising deoxyribose | Sony Group Corporation (JP) | 2024-06-11 | — | — | US | disclosed |
| WO-2024118840-A1 | FUSED PYRIMIDINES AS MASP-2 INHIBITORS | OMEROS CORPORATION (US) | 2024-06-06 | — | — | WO | disclosed |
| WO-2024110803-A1 | POLYMERIC COMPOUNDS COMPRISING ANTINEOPLASTIC AGENTS | Sony Group Corporation (JP) | 2024-05-30 | — | — | WO | disclosed |
| US-11981820-B2 | Ultra bright dimeric or polymeric dyes | Sony Group Corporation (JP) | 2024-05-14 | — | — | US | disclosed |
| US-8415370-B2 | Spiro-oxindole compounds and their uses as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2013-04-09 | — | — | US | disclosed |
| US-20120295897-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2012-11-22 | — | — | US | disclosed |
| US-8101647-B2 | Spiro-oxindole compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2012-01-24 | — | — | US | disclosed |
| US-20110144139-A1 | HEPSIN INHIBITORS | FRED HUTCHINSON CANCER RESEARCH CENTER | 2011-06-16 | — | — | US | disclosed |
| US-20110112162-A9 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2011-05-12 | — | — | US | disclosed |
| US-20100099728-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2010-04-22 | — | — | US | disclosed |
| CN-101014594-A | Piperidine derivatives as renin inhibitors | SPEEDEL EXPERIMENTA AG (CH) | 2007-08-08 | — | — | CN | disclosed |
| EP-0620813-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF AND ANGIOTENSIN II | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-10-26 | — | — | EP | disclosed |
| WO-1993014069-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF AND ANGIOTENSIN II | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228499-A1 | MASP-2 INHIBITORS AND METHODS OF USE | MASP2, SPINT2, SERPINB1 | CES1 1728/4885PTPRC 1730/4885 |
| US-11981820-B2 | Ultra bright dimeric or polymeric dyes | IK, MRPS2, UFM1 | CES1 4474/4885PTPRC 3331/4885 |
| US-20110112162-A9 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | TRPV3, TRPV1, TRPC3 | CES1 3034/4885PTPRC 1189/4885 |
| US-20110144139-A1 | HEPSIN INHIBITORS | HPN, TMPRSS2, SPINT2 | CES1 232/4885PTPRC 2484/4885 |
| US-20240207423-A1 | PROGAMMABLE POLYMERIC DRUGS | OPRM1, CHRM1, TUBB3 | CES1 1331/4885PTPRC 2179/4885 |
| US-12006438-B2 | Polymeric dyes with linker groups comprising deoxyribose | H1-0, POLM, H1-2 | CES1 3979/4885PTPRC 4177/4885 |
| US-20100099728-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | TRPV3, TRPV1, TRPC3 | CES1 3034/4885PTPRC 1189/4885 |
| US-20120295897-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | TRPV3, TRPC3, TRPV1 | CES1 3090/4885PTPRC 1125/4885 |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | CES1 1587/4885PTPRC 1071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.