Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835753 | 0.88 | KAT2B (0.39) | DRD2DRD4DRD3KAT2BCHRM1 | |
| SCHEMBL10118459 | 0.85 | DRD2 (0.48) | DRD2DRD4DRD3KAT2BSLC2A1 | |
| Piperazine SCHEMBL5524481 | 0.85 | HTR3E (0.31) | TLR8TLR7KDM4EGAA | |
| SCHEMBL1841847 | 0.82 | KAT2B (0.51) | DRD2DRD4DRD3KAT2BSLC2A1 | |
| SCHEMBL1841548 | 0.81 | KAT2B (0.48) | DRD3KAT2BACHEKDM4EGAA | |
| Hydrochloric Acid SCHEMBL1839969 | 0.81 | KAT2B (0.50) | DRD2DRD4DRD3KAT2BSLC2A1 | |
| SCHEMBL3841138 | 0.81 | VCP (0.32) | DRD2DRD4DRD3CHRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL1842069 | 0.81 | KAT2B (0.47) | DRD3KAT2BACHEKDM4EGAA | |
| SCHEMBL1842861 | 0.81 | KAT2B (0.49) | KAT2BACHEKDM4EGAAHSD17B10 | |
| SCHEMBL3518957 | 0.80 | CYP2D6 (0.33) | CHRM1CHRM2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464424-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | OREAL (FR) | 2019-09-25 | — | — | EP | claimed |
| EP-2651516-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | claimed |
| EP-2155153-B1 | DYEING COMPOSITION COMPRISING A SPECIFIC AMINOPYRAZOLOPYRIDINE OXIDATION BASE, A COUPLER AND A SPECIFIC SURFACTANT | L'ORÉAL (FR) | 2017-03-01 | — | — | EP | claimed |
| EP-2651935-B1 | DYEING COMPOSITION COMPRISING A FATTY SUBSTANCE, A PYRAZOLOPYRIDINE OXIDATION BASE AND A COUPLER | ORÉAL L (FR) | 2016-11-23 | — | — | EP | claimed |
| EP-1792903-B1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | OREAL (FR) | 2009-10-14 | — | — | EP | claimed |
| US-7578856-B2 | Dyeing compositions comprising at least one aminopyrazolopyridine oxidation base, at least one coupler and at least one C4-C30 polyol and methods and use thereof | L'OREAL S.A. (FR) | 2009-08-25 | — | — | US | claimed |
| EP-1992331-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | L'Oreal (FR) | 2008-11-19 | — | — | EP | claimed |
| EP-1992330-A2 | Process for colouring keratinous fibres comprising the application of an aminopyrazolopyridine oxidation base in the absence of oxidizing agent | L'Oreal (FR) | 2008-11-19 | — | — | EP | claimed |
| EP-1992329-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base and a specific associative polymer | L'Oréal (FR) | 2008-11-19 | — | — | EP | claimed |
| US-11730688-B2 | Composition for dyeing the hair, comprising a heterocyclic oxidation base and a 2-amino-5-ethylphenol coupler | L'OREAL (FR) | 2023-08-22 | — | — | US | disclosed |
| EP-2464424-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | OREAL (FR) | 2019-09-25 | — | — | EP | disclosed |
| EP-2464424-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | OREAL (FR) | 2019-09-25 | — | — | EP | disclosed |
| US-20170354580-A1 | DYE COMPOSITION COMPRISING A PARA-PHENYLENEDIAMINE OXIDATION BASE AND A HETEROCYCLIC OXIDATION BASE | L'OREAL (FR) | 2017-12-14 | — | — | US | disclosed |
| EP-2651516-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | disclosed |
| EP-1992331-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992331-A1 | Dyeing composition comprising an aminopyrazolopyridine oxidation base, a coupler and a specific polyol | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992330-A2 | Process for colouring keratinous fibres comprising the application of an aminopyrazolopyridine oxidation base in the absence of oxidizing agent | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992330-A2 | Process for colouring keratinous fibres comprising the application of an aminopyrazolopyridine oxidation base in the absence of oxidizing agent | L'Oreal (FR) | 2008-11-19 | — | — | EP | disclosed |
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'OREAL S.A. (FR) | 2007-06-21 | — | — | US | disclosed |
| EP-1792903-A1 | Composition for the dyeing of keratin fibres comprising at least one cationic 3-amino-pyrazolopyridine derivative | L'OREAL (FR) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | KRT18, COX5A, PNPO | DRD2 3458/4885DRD4 2760/4885DRD3 2868/4885 |
| US-11730688-B2 | Composition for dyeing the hair, comprising a heterocyclic oxidation base and a 2-amino-5-ethylphenol coupler | KRT18, COX5B, COX5A | DRD2 1903/4885DRD4 1516/4885DRD3 2339/4885 |
| US-20170354580-A1 | DYE COMPOSITION COMPRISING A PARA-PHENYLENEDIAMINE OXIDATION BASE AND A HETEROCYCLIC OXIDATION BASE | KRT18, DSG1, SQOR | DRD2 1764/4885DRD4 1607/4885DRD3 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.