Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.56 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.56 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.56 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TCF4 | P15884 | 2/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.54 |
| ▸ | LOX | P28300 | 1/20 | 0.51 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 2/20 | 0.48 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20791898 | 0.90 | TSHR (0.55) | ALDH1A1KDM4EKMT2ACA12CA1 | |
| Tetraphenylphosphonium SCHEMBL3942403 | 0.87 | KMT2A (0.49) | ALDH1A1KDM4EKMT2ACA12CA1 | |
| SCHEMBL28682355 | 0.86 | CA1 (0.50) | ALDH1A1KDM4EKMT2ACA12CA1 | |
| Sulfuric Acid SCHEMBL11211295 | 0.86 | POLB (0.60) | ALDH1A1KDM4EKMT2ACA12CA1 | |
| SCHEMBL2884607 | 0.84 | LOX (0.66) | ALDH1A1KDM4EKMT2ACA12CA1 | |
| SCHEMBL3944685 | 0.84 | KDM4E (0.46) | ALDH1A1KDM4EKMT2ACA12CA1 | |
| SCHEMBL3293304 | 0.83 | POLB (0.57) | ALDH1A1KDM4EKMT2ACA12CA1 | |
| SCHEMBL1100084 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4EKMT2ACA12CA1 | |
| SCHEMBL2651155 | 0.83 | POLB (0.61) | ALDH1A1KDM4EKMT2ACA12CA1 | |
| SCHEMBL9008002 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4EKMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448997-B1 | MODIFIED POLYAMIDE COMPOSITION | RHODIA OPERATIONS (FR) | 2018-10-03 | — | — | EP | claimed |
| EP-2576658-B1 | SULFONATE-MODIFIED POLYAMIDE HAVING IMPROVED BARRIER PROPERTIES | RHODIA OPERATIONS S A (FR) | 2018-07-11 | — | — | EP | claimed |
| US-9732222-B2 | Modified polyamide composition | RHODIA OPERATIONS (FR) | 2017-08-15 | — | — | US | claimed |
| US-20130150524-A1 | SULFONATE-MODIFIED POLYAMIDE HAVING IMPROVED BARRIER PROPERTIES | RHODIA OPERATIONS (FR) | 2013-06-13 | — | — | US | claimed |
| EP-2576658-A1 | SULFONATE-MODIFIED POLYAMIDE HAVING IMPROVED BARRIER PROPERTIES | Rhodia Operations S.A. (FR) | 2013-04-10 | — | — | EP | claimed |
| US-20120172521-A1 | MODIFIED POLYAMIDE COMPOSITION | RHODIA OPERATIONS (FR) | 2012-07-05 | — | — | US | claimed |
| EP-2448997-A1 | MODIFIED POLYAMIDE COMPOSITION | Rhodia Opérations (FR) | 2012-05-09 | — | — | EP | claimed |
| WO-2011147739-A1 | SULFONATE-MODIFIED POLYAMIDE HAVING IMPROVED BARRIER PROPERTIES | RHODIA OPERATIONS (FR) | 2011-12-01 | — | — | WO | claimed |
| WO-2011000763-A1 | MODIFIED POLYAMIDE COMPOSITION | RHODIA OPERATIONS (FR) | 2011-01-06 | — | — | WO | claimed |
| CN-117229257-A | Meta-sulfamoyl benzamide compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-111607076-A | Antistatic polyester composition, preparation method thereof and polyester film | 东丽纤维研究所（中国）有限公司 | 2020-09-01 | — | — | CN | disclosed |
| EP-2448997-B1 | MODIFIED POLYAMIDE COMPOSITION | RHODIA OPERATIONS (FR) | 2018-10-03 | — | — | EP | disclosed |
| EP-2576658-B1 | SULFONATE-MODIFIED POLYAMIDE HAVING IMPROVED BARRIER PROPERTIES | RHODIA OPERATIONS S A (FR) | 2018-07-11 | — | — | EP | disclosed |
| EP-2448998-B1 | MODIFIED POLYAMIDE, PREPARATION METHOD THEREOF AND ARTICLE OBTAINED FROM SAID POLYAMIDE | RHODIA OPERATIONS (FR) | 2018-04-25 | — | — | EP | disclosed |
| WO-2011000764-A1 | MODIFIED POLYAMIDE, PREPARATION METHOD THEREOF AND ARTICLE OBTAINED FROM SAID POLYAMIDE | RHODIA OPERATIONS (FR) | 2011-01-06 | — | — | WO | disclosed |
| WO-2011000763-A1 | MODIFIED POLYAMIDE COMPOSITION | RHODIA OPERATIONS (FR) | 2011-01-06 | — | — | WO | disclosed |
| US-5488123-A | SULFONATED; TEXTILE FINISHING; ANTISOILANTS, ANTISTATIC AGENTS | CASSELLA AG (DE) | 1996-01-30 | — | — | US | disclosed |
| WO-1993007198-A1 | SULFONATED POLYESTERS AND THEIR USE IN COMPOSTABLE PRODUCTS SUCH AS DISPOSABLE DIAPERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-04-15 | — | — | WO | disclosed |
| US-5171308-A | Polyethylene terephthalate copolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0023664-B1 | PROCESS FOR PRODUCING THE SAME OF HOLLOW WATER-ABSORBING POLYESTER FILAMENTS | TEIJIN LIMITED (JP) | 1985-12-04 | — | — | EP | disclosed |