Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 3/20 | 0.47 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 9/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL28435351 | 0.96 | CA12 (0.42) | CA12CA9CA7CA14CXCR4 | |
| SCHEMBL28428673 | 0.95 | CA12 (0.46) | CA12CA9CA7CA14CXCR4 | |
| SCHEMBL5458450 | 0.89 | CA12 (0.50) | CA12CA9CA7CA14CXCR4 | |
| SCHEMBL9518428 | 0.82 | CXCR4 (0.45) | CA12CA9CA7CA14CXCR4 | |
| SCHEMBL37872 | 0.79 | CXCR4 (0.46) | CA12CA7CA14CXCR4CXCL12 | |
| SCHEMBL918578 | 0.79 | CXCR4 (0.46) | CA12CA7CA14CXCR4CXCL12 | |
| SCHEMBL3904237 | 0.79 | CA1 (0.45) | CA12CA7CA14CXCR4CXCL12 | |
| SCHEMBL21518374 | 0.79 | CXCR4 (0.46) | CA12CA7CA14CXCR4CXCL12 | |
| SCHEMBL3904234 | 0.79 | CXCR4 (0.42) | CA12CA7CA14CXCR4CXCL12 | |
| SCHEMBL3857080 | 0.78 | CXCR4 (0.45) | CA12CA7CA14CXCR4CXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116556070-B | Enzymatic anti-felting finishing method for low-strength-loss colored wool fabric | 江南大学 | 2025-06-03 | — | — | CN | claimed |
| CN-118421250-A | Heat-activated aqueous polyurethane adhesive and application method thereof | 黎明化工研究设计院有限责任公司 | 2024-08-02 | — | — | CN | claimed |
| EP-4263690-A1 | LONG-TERM FIRE RETARDANT WITH CORROSION INHIBITORS AND METHODS FOR MAKING AND USING SAME | FRS Group, LLC (US) | 2023-10-25 | — | — | EP | claimed |
| CN-116556070-A | Enzymatic anti-felting finishing method for low-strength-loss colored wool fabric | 江南大学 | 2023-08-08 | — | — | CN | claimed |
| CN-113956766-B | Long-activation-period water-based bi-component polyurethane coating and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-11-08 | — | — | CN | claimed |
| WO-2022132962-A1 | LONG-TERM FIRE RETARDANT WITH CORROSION INHIBITORS AND METHODS FOR MAKING AND USING SAME | FRS GROUP, LLC (US) | 2022-06-23 | — | — | WO | claimed |
| US-12398099-B2 | Multi-aziridine compound | COVESTRO (NETHERLANDS) B.V. (NL) | 2025-08-26 | — | — | US | disclosed |
| CN-116556070-B | Enzymatic anti-felting finishing method for low-strength-loss colored wool fabric | 江南大学 | 2025-06-03 | — | — | CN | disclosed |
| US-12281072-B2 | Multi-aziridine compound | COVESTRO (NETHERLANDS) B.V. (NL) | 2025-04-22 | — | — | US | disclosed |
| CN-119144369-A | Composite polyurea sulfonate lubricating grease and preparation method thereof | 亚培烯科技(上海)有限公司 | 2024-12-17 | — | — | CN | disclosed |
| EP-4263690-A1 | LONG-TERM FIRE RETARDANT WITH CORROSION INHIBITORS AND METHODS FOR MAKING AND USING SAME | FRS Group, LLC (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-116556070-A | Enzymatic anti-felting finishing method for low-strength-loss colored wool fabric | 江南大学 | 2023-08-08 | — | — | CN | disclosed |
| US-20230127229-A1 | MULTI-AZIRIDINE COMPOUND | COVESTRO (NETHERLANDS) B.V. (NL) | 2023-04-27 | — | — | US | disclosed |
| EP-1743943-A1 | PROCESS FOR PRODUCING L-FUCULOSE AND PROCESS FOR PRODUCING L-FUCOSE | Ajinomoto Co., Inc. (JP) | 2007-01-17 | — | — | EP | disclosed |
| US-20010036654-A1 | Canola acetyl-CoA carboxylase compositions and methods of use | ARCH DEVELOPMENT CORPORATION (US) | 2001-11-01 | — | — | US | disclosed |
| US-6177267-B1 | AMINO ACID SEQUENCE OF ACETYL-COENZYME A CARBOXYLASE; FOR TRANSGENIC PLANTS WITH INCREASED OR DECREASED HERBICIDE RESISTANCE; FOR SCREENING SAMPLES FOR HERBICIDE RESISTANCE | ARCH DEVELOPMENT CORP. | 2001-01-23 | — | — | US | disclosed |
| US-5910626-A | NUCLEIC ACIDS ENCODING POLYPEPTIDES PARTICIPATING IN THE CARBOXYLATION OF ACETYL-COA, E.G. A SUBUNIT, BIOTIN CARBOXYLASE CARRIER PROTEIN; HERBICIDE RESISTANCE; INCREASED OIL PRODUCTION IN PLANT TISSUE | ARCH DEVELOPMENT CORPORATION (US) | 1999-06-08 | — | — | US | disclosed |
| US-5801233-A | DNA SEGMENTS AND CELLS FOR ACETYL COA CARBOXYLASE AND NUCLEIC ACID SEGMENTS | ARCH DEVELOPMENT CORPORATION (US) | 1998-09-01 | — | — | US | disclosed |
| EP-0820514-A2 | ACETYL-CoA CARBOXYLASE COMPOSITIONS AND METHODS OF USE | ARCH DEVELOPMENT CORPORATION (US) | 1998-01-28 | — | — | EP | disclosed |
| WO-1996032484-A2 | ACETYL-CoA CARBOXYLASE COMPOSITIONS AND METHODS OF USE | ARCH DEVELOPMENT CORPORATION (US) | 1996-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12281072-B2 | Multi-aziridine compound | HRH3, QDPR, HRH4 | CA12 1942/4885CA1 2307/4885CA2 2044/4885 |
| US-12398099-B2 | Multi-aziridine compound | HRH3, QDPR, HRH4 | CA12 2407/4885CA1 2633/4885CA2 2194/4885 |
| US-20230127229-A1 | MULTI-AZIRIDINE COMPOUND | HRH3, QDPR, HRH4 | CA12 1942/4885CA1 2307/4885CA2 2044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.