SCHEMBL386233

SCHEMBL386233

[CH]=CC(C)CCCC(C)CCCC(C)CCCC(C)C

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
BLM P54132 1/20 0.43
PTPN1 P18031 3/20 0.42
MEN1 O00255 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42
KMT2A Q03164 1/20 0.42
PTPN2 P17706 1/20 0.33
CDC25B P30305 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL386906 1.00 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL23113042 1.00 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL386001 0.93 LMNA (0.46) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL538230 0.79 LMNA (0.93) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL29662067 0.79 LMNA (0.93) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL8672325 0.79 LMNA (0.93) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL20928 0.79 LMNA (0.93) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL385823 0.79 LMNA (0.34) LMNA
SCHEMBL386654 0.79 LMNA (0.34) LMNA
SCHEMBL387276 0.79 LMNA (0.34) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11970510-B2 Catalyst component and catalyst for olefin polymerization, and application thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-04-30 US disclosed
EP-4353262-A1 NOVEL COMPOUND HAVING INHIBITORY ACTIVITY AGAINST PENDRIN, AND PHARMACEUTICAL USES THEREOF UIF (University Industry Foundation), Yonsei University (KR) 2024-04-17 EP disclosed
CN-117794577-A Novel compound with inhibitory activity on Pan Telin and pharmaceutical application thereof 延世大学校产学协力团 2024-03-29 CN disclosed
EP-3483186-B1 MODIFIED CELLULOSE NANOFIBER AND RUBBER COMPOSITION INCLUDING THE SAME JUJO PAPER CO LTD (JP) 2023-06-07 EP disclosed
US-20230096466-A1 NEW METHOD OF SYNTHESIS OF CHITOSAN DERIVATIVES AND USES THEREOF NOVOCHIZOL SA (CH) 2023-03-30 US disclosed
CN-115516012-A Novel synthesis method and application of chitosan derivative 诺和席卓股份有限公司 2022-12-23 CN disclosed
WO-2022260494-A1 NOVEL COMPOUND HAVING INHIBITORY ACTIVITY AGAINST PENDRIN, AND PHARMACEUTICAL USES THEREOF 연세대학교 산학협력단 2022-12-15 WO disclosed
US-20220390458-A1 FLUORESCENT PROBE AND APPLICATIONS THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2022-12-08 US disclosed
CN-112707989-B Plasticizer-free ethylene-propylene random copolymer and application thereof 中国石油化工股份有限公司 2022-08-19 CN disclosed
CN-112707991-B Ethylene-propylene random copolymer and preparation method thereof 中国石油化工股份有限公司 2022-08-19 CN disclosed
US-6964976-B2 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2005-11-15 US disclosed
US-20050043386-A1 Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these SANKYO COMPANY, LIMITED (JP) 2005-02-24 US disclosed
EP-1505068-A1 PYRAZOLO (1,5-a) PYRIMIDINE DERIVATIVE AND NAD(P)H OXIDASE INHIBITOR CONTAINING THE SAME SHIONOGI & CO., LTD. (JP) 2005-02-09 EP disclosed
EP-1471054-A1 AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE Sankyo Company, Limited (JP) 2004-10-27 EP disclosed
US-20040132784-A1 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2004-07-08 US disclosed
US-6723745-B2 PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL SANKYO COMPANY, LIMITED (JP) 2004-04-20 US disclosed
US-20030236297-A1 Amino alcohol derivatives SANKYO COMPANY, LIMITED (JP) 2003-12-25 US disclosed
EP-1300405-A1 AMINO ALCOHOL DERIVATIVES Sankyo Company, Limited (JP) 2003-04-09 EP disclosed
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed
EP-1057825-A1 ISOFLAVANE DERIVATIVES AND IMMUNOPOTENTIATING COMPOSITIONS CONTAINING THE SAME SHIONOGI & CO., LTD. (JP) 2000-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030236297-A1 Amino alcohol derivatives CD4, ADH1C, ADH1A LMNA 3703/4885BLM 4551/4885PTPN1 2617/4885
US-20230096466-A1 NEW METHOD OF SYNTHESIS OF CHITOSAN DERIVATIVES AND USES THEREOF CHIA, CHIT1, CHI3L2 LMNA 1344/4885BLM 2825/4885PTPN1 3999/4885
US-20050043386-A1 Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these PHOSPHO1, CD4, FCGRT LMNA 4143/4885BLM 4661/4885PTPN1 624/4885
US-20040132784-A1 Amino alcohol derivatives CD4, ADH1C, ADH1A LMNA 3703/4885BLM 4551/4885PTPN1 2617/4885
US-11970510-B2 Catalyst component and catalyst for olefin polymerization, and application thereof OGDH, MDH1, MDH2 LMNA 4198/4885BLM 1689/4885PTPN1 4734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.