Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.46 |
| ▸ | RAF1 known ✓ | P04049 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | MAOA | P21397 | 4/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | RECQL | P46063 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | APEX1 | P27695 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | BCL2 | P10415 | 2/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.63 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL16937078 | 0.99 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Edetic Acid SCHEMBL4005959 | 0.99 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Edetic Acid SCHEMBL5608586 | 0.84 | MAPT (0.63) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Athraquinones A SCHEMBL21114402 | 0.80 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Athraquinones A SCHEMBL29373337 | 0.80 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Athraquinones A SCHEMBL4972786 | 0.80 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Athraquinones A SCHEMBL18614 | 0.80 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Athraquinones A SCHEMBL4249545 | 0.78 | MAPT (0.83) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Athraquinones A SCHEMBL10533977 | 0.78 | MAPT (0.83) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| Athraquinones A SCHEMBL7839563 | 0.78 | MAPT (0.96) | MAPTMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115718097-A | Detection reagent for fluorine ion online monitoring instrument and preparation method thereof | 湖南环信科技有限公司 | 2023-02-28 | — | — | CN | claimed |
| US-11193883-B2 | Kits for detecting content of fluoride ions in microsamples | HARBIN MEDICAL UNIVERSITY (CN) | 2021-12-07 | — | — | US | claimed |
| US-11041800-B2 | Method for detecting content of fluoride ions in microsamples | HARBIN MEDICAL UNIVERSITY (CN) | 2021-06-22 | — | — | US | claimed |
| CN-108121113-B | Optical unit and display device having the same | 乐金显示有限公司 | 2021-05-14 | — | — | CN | claimed |
| CN-112700906-A | Solidified high-conductivity silver paste prepared from particle-free conductive silver ink | 江苏碳导材料科技有限公司 | 2021-04-23 | — | — | CN | claimed |
| US-20200080933-A1 | KITS FOR DETECTING CONTENT OF FLUORIDE IONS IN MICROSAMPLES | HARBIN MEDICAL UNIVERSITY (CN) | 2020-03-12 | — | — | US | claimed |
| US-20200080932-A1 | METHOD FOR DETECTING CONTENT OF FLUORIDE IONS IN MICROSAMPLES | HARBIN MEDICAL UNIVERSITY (CN) | 2020-03-12 | — | — | US | claimed |
| US-10401677-B2 | Optical unit and display device having the same | LG DISPLAY CO., LTD. (KR) | 2019-09-03 | — | — | US | claimed |
| US-10401320-B2 | Method of fabricating 3-dimensional transistor sensor, the sensor and sensor array thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2019-09-03 | — | — | US | claimed |
| US-20190072516-A1 | METHOD OF FABRICATING 3-DIMENSIONAL TRANSISTOR SENSOR, THE SENSOR AND SENSOR ARRAY THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2019-03-07 | — | — | US | claimed |
| WO-2006112827-A1 | RAPID ANALYSIS OF FUNCTIONAL FLUIDS | THE LUBRIZOL CORPORATION (US) | 2006-10-26 | — | — | WO | claimed |
| US-20060003459-A1 | Adding boronic acid-derivative chiral receptor to indicator such as of alizarin red S, adding analyte such as alpha -hydroxyacid or amino acid, inspection of color with the naked eye, spectrographic measurement, or mathematical calculation | UNIVERSITY OF TEXAS AT AUSTIN (US) | 2006-01-05 | — | — | US | claimed |
| US-20050227369-A1 | Rapid analysis of functional fluids | THE LUBRIZOL CORPORATION, A CORPORATION OF THE STATE OF OHIO (US) | 2005-10-13 | — | — | US | claimed |
| WO-2004004449-A1 | USE OF ONE OR MORE CHEMICAL COMPOUND FOR MARKING OF FISH | VETERINÆRMEDISINSK OPPDRAGSSENTER AS (NO) | 2004-01-15 | — | — | WO | claimed |
| US-6495302-B1 | MIXING LATEX WITH COLORANT; HEATING | XEROX CORPORATION | 2002-12-17 | — | — | US | claimed |
| US-20020187416-A1 | Toner coagulant processes | XEROX CORPORATION | 2002-12-12 | — | — | US | claimed |
| US-20020187415-A1 | TONER COAGULANT PROCESSES | XEROX CORPORATION | 2002-12-12 | — | — | US | claimed |
| EP-0348509-B1 | ANTI-RETROVIRAL DRUG | TSUMURA & CO. (JP) | 1993-03-24 | — | — | EP | claimed |
| EP-0348509-A1 | ANTI-RETROVIRAL DRUG | TSUMURA & CO. (JP) | 1990-01-03 | — | — | EP | claimed |
| US-3957438-A | Detecting fluorite in a solid rock sample | LOST RIVER MINING CORPORATION LIMITED (CA) | 1976-05-18 | — | — | US | claimed |