Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823426 | 0.97 | MAOA (0.44) | MAOAMAOBMAPKAPK2ACSL1SMN1; SMN2 | |
| SCHEMBL3890326 | 0.97 | MAOA (0.44) | MAOAMAOBMAPKAPK2ACSL1SMN1; SMN2 | |
| Lithium Ion SCHEMBL3898744 | 0.97 | MAOA (0.44) | MAOAMAOBMAPKAPK2ACSL1SMN1; SMN2 | |
| SCHEMBL672719 | 0.97 | MAOA (0.44) | MAOAMAOBMAPKAPK2ACSL1SMN1; SMN2 | |
| SCHEMBL673852 | 0.97 | MAOA (0.44) | MAOAMAOBMAPKAPK2ACSL1SMN1; SMN2 | |
| SCHEMBL11512376 | 0.97 | MAOA (0.44) | MAOAMAOBMAPKAPK2ACSL1SMN1; SMN2 | |
| SCHEMBL150427 | 0.97 | MAOA (0.44) | MAOAMAOBMAPKAPK2ACSL1SMN1; SMN2 | |
| SCHEMBL11826523 | 0.97 | MAOA (0.44) | MAOAMAOBMAPKAPK2ACSL1SMN1; SMN2 | |
| SCHEMBL673811 | 0.97 | MAOA (0.44) | MAOAMAOBMAPKAPK2ACSL1SMN1; SMN2 | |
| Zinc Ion SCHEMBL15158099 | 0.97 | MAOA (0.44) | MAOAMAOBMAPKAPK2ACSL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109374778-B | Method for determining organic impurities in 2-mercaptobenzimidazole | 长沙理工大学 | 2021-08-10 | — | — | CN | claimed |
| US-20190002421-A1 | PROCESS AND NOVEL POLYMORPHIC FORM OF VORTIOXETINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | APICORE US LLC (US) | 2019-01-03 | — | — | US | claimed |
| EP-3363935-B1 | FIBER FOR RUBBER REINFORCEMENT, RUBBER-FIBER COMPOSITE, AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2025-03-12 | — | — | EP | disclosed |
| US-20250064844-A1 | N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO | EMORY UNIVERSITY | 2025-02-27 | — | — | US | disclosed |
| US-20240391909-A1 | DISULFIDE COMPOUND, POLYSULFIDE COMPOUND, AND USE THEREOF | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-11-28 | — | — | US | disclosed |
| EP-4424672-A1 | DISULFIDE COMPOUND, POLYSULFIDE COMPOUND, AND USE THEREOF | Kumiai Chemical Industry Co., Ltd. (JP) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023228463-A1 | METHOD FOR PRODUCING RUBBER COMPOSITION, RUBBER COMPOSITION AND TIRE | 株式会社ブリヂストン | 2023-11-30 | — | — | WO | disclosed |
| WO-2023074828-A1 | DISULFIDE COMPOUND, POLYSULFIDE COMPOUND, AND USE THEREOF | クミアイ化学工業株式会社 | 2023-05-04 | — | — | WO | disclosed |
| CN-113831269-B | Synthesis method of vinyl dithiocarbamate compound | 台州学院 | 2023-04-07 | — | — | CN | disclosed |
| EP-3266817-B1 | RUBBER COMPOSITION FOR TIRES, AND TIRE | BRIDGESTONE CORP (JP) | 2023-04-05 | — | — | EP | disclosed |
| CN-115666587-A | N4-hydroxycytidine and derivatives and related antiviral uses thereof | 埃默里大学 | 2023-01-31 | — | — | CN | disclosed |
| EP-1051461-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR, William C. (US) | 2000-11-15 | — | — | EP | disclosed |
| US-6054414-A | HERBICIDE | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-25 | — | — | US | disclosed |
| WO-1999066009-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR WILLIAM C (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0954558-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR, William C. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1998026028-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR WILLIAM C (US) | 1998-06-18 | — | — | WO | disclosed |
| US-4801714-A | FROM CORRESPONDING UREA, PHOSPHORUS OXYCHLORIDE, THIOLATING AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-01-31 | — | — | US | disclosed |
| US-4772610-A | BLOCKING AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | disclosed |
| US-4556415-A | POST-EMERGENCE | MONSANTO COMPANY (US) | 1985-12-03 | — | — | US | disclosed |
| US-3978225-A | ANTIPROSTAGLANDIN, ANTIDIARRHEA | SMITHKLINE CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002421-A1 | PROCESS AND NOVEL POLYMORPHIC FORM OF VORTIOXETINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | CHRNA1, ADH1A, CHRNB1 | MAOA 1161/4885MAOB 733/4885MAPKAPK2 2687/4885 |
| US-20240391909-A1 | DISULFIDE COMPOUND, POLYSULFIDE COMPOUND, AND USE THEREOF | STS, SQOR, PRDX2 | MAOA 3546/4885MAOB 3254/4885MAPKAPK2 618/4885 |
| US-20250064844-A1 | N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO | TYMP, MTAP, DCTD | MAOA 2401/4885MAOB 2734/4885MAPKAPK2 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.