Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392687 | 1.00 | PARP1 (0.56) | PARP1MAOBCYP19A1MAOAALDH1A1 | |
| SCHEMBL388480 | 0.88 | PARP1 (0.53) | PARP1MAOBCYP19A1MAOAALDH1A1 | |
| SCHEMBL14120724 | 0.88 | BCL2L1 (0.53) | PARP1MAOBCYP19A1MAOAALDH1A1 | |
| SCHEMBL21772776 | 0.86 | PARP1 (0.51) | PARP1MAOBCYP19A1MAOAALDH1A1 | |
| SCHEMBL5793477 | 0.78 | MAOA (0.56) | PARP1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL5541367 | 0.76 | ALDH1A1 (0.41) | PARP1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL31032281 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTALOX15HSD17B10LMNA | |
| SCHEMBL569778 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTALOX15HSD17B10LMNA | |
| SCHEMBL17613901 | 0.75 | ALDH1A1 (0.42) | PARP1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL1658784 | 0.74 | PARP1 (0.47) | PARP1MAOBCYP19A1MAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 550 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920635-B | Preparation method of 4-hydroxy-1-indenone | 郑州原理医药研究院有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-113248356-B | Industrial production method of 4-hydroxy-1-indanone | 宣城菁科生物科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-114920635-A | Preparation method of 4-hydroxy-1-indanone | 郑州原理生物科技有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-113248356-A | Industrial production method of 4-hydroxy-1-indanone | 宣城菁科生物科技有限公司 | 2021-08-13 | — | — | CN | claimed |
| CN-108101024-B | Method for preparing carbon nano tube by mixed gas source | 江苏天奈科技股份有限公司 | 2020-07-10 | — | — | CN | claimed |
| WO-2009071799-A1 | PROCESS FOR THE SYNTHESIS OF 4-BENZOFURANCARBOXYLIC ACID | ZACH SYSTEM (FR) | 2009-06-11 | — | — | WO | claimed |
| US-20090131688-A1 | METHOD FOR THE SYNTHESIS OF 4-BENZOFURAN-CARBOXYLIC ACID | ZACH SYSTEM (FR) | 2009-05-21 | — | — | US | claimed |
| US-5618982-A | SIMPLE INDUSTRIAL PROCESS OF CATALYZING IN PRESENCE OF METALLIC PHOSPHATES | RHONE-POULENC CHIMIE (FR) | 1997-04-08 | — | — | US | claimed |
| JP-56108723-A | — | — | None | — | — | JP | disclosed |
| US-12590062-B2 | PD-1/PD-L1 inhibitors | GILEAD SCIENCES, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| US-20250360486-A1 | Biorefining Method | LICELLA PTY LTD (AU) | 2025-11-27 | — | — | US | disclosed |
| EP-4619386-A1 | ARYL THIOETHERS AS HIF-2ALPHA INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-09-24 | — | — | EP | disclosed |
| US-12421193-B2 | GPR52 modulators and methods of use | NEUROCRINE BIOSCIENCES, INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-12409437-B2 | Biorefining method | LICELLA PTY LTD (AU) | 2025-09-09 | — | — | US | disclosed |
| US-4322414-A | MITICIDES; APHIDICIDES; LARVICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0043971-A1 | Indanoneoxyalkylpiperazine derivatives, the preparation thereof and pharmaceutical compositions containing the same | BASF Aktiengesellschaft (DE) | 1982-01-20 | — | — | EP | disclosed |
| JP-S56108723-A | PREPARATION OF INDENE DERIVATIVE | IWAKI SEIYAKU KK | 1981-08-28 | — | — | JP | disclosed |
| US-4109088-A | ANTIDEPRESSANTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1978-08-22 | — | — | US | disclosed |
| US-4076726-A | Amidino-hydrazone derivatives | AKZONA INCORPORATED (US) | 1978-02-28 | — | — | US | disclosed |
| US-4028380-A | Hydrazino-imidazole derivatives | AKZONA INCORPORATED (US) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131688-A1 | METHOD FOR THE SYNTHESIS OF 4-BENZOFURAN-CARBOXYLIC ACID | COASY, HSD17B12, ALDH18A1 | PARP1 1500/4885MAOB 335/4885CYP19A1 7/4885 |
| US-12590062-B2 | PD-1/PD-L1 inhibitors | CD274, PDCD1LG2, PDCD1 | PARP1 401/4885MAOB 1633/4885CYP19A1 1342/4885 |
| US-12421193-B2 | GPR52 modulators and methods of use | GPR52, GPR68, GPR35 | PARP1 4171/4885MAOB 947/4885CYP19A1 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.