SCHEMBL4884737

SCHEMBL4884737

COC(C(=O)O)=C(c1ccccc1C(C)C)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 2/20 0.43
KCNK9 Q9NPC2 2/20 0.43
LMNA P02545 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 1/20 0.39
GAA P10253 3/20 0.39
LPAR1 Q92633 3/20 0.38
ATM Q13315 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 2/20 0.37
ALOX15 P16050 1/20 0.36
BCL2 P10415 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4279863 0.80 TSHR (0.48) LMNAKMT2AKDM4EHPGDGAA
SCHEMBL38971 0.78 LMNA (0.40) KCNK3KCNK9LMNAKMT2AHPGD
Hydrogen Peroxide SCHEMBL28473316 0.75 TSHR (0.57) KCNK3KCNK9LMNAKMT2AKDM4E
SCHEMBL254882 0.73 TSHR (0.59) KCNK3KCNK9LMNAKMT2AKDM4E
SCHEMBL5237181 0.71 TSHR (0.52) KCNK3KCNK9LMNAKMT2AKDM4E
Hydrogen Peroxide SCHEMBL9514730 0.70 ALDH1A1 (0.59) LMNAKMT2AKDM4EHPGDHSD17B10
Benzene SCHEMBL28132022 0.70 ALDH1A1 (0.59) LMNAKMT2AKDM4EHPGDHSD17B10
SCHEMBL254364 0.70 ALDH1A1 (0.59) LMNAKMT2AKDM4EHPGDHSD17B10
SCHEMBL29657201 0.70 ALDH1A1 (0.59) LMNAKMT2AKDM4EHPGDHSD17B10
SCHEMBL26856293 0.69 KCNK3 (0.54) KCNK3KCNK9LMNAKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200261748-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING AN AQUEOUS PHASE AND A LOW MELTING POINT APOLAR WAX L'OREAL (FR) 2020-08-20 US disclosed
EP-2985018-A1 ANTI-DISCOLORATION COMPOSITION Sensient Cosmetic Technologies (FR) 2016-02-17 EP disclosed
EP-1755543-B1 ANTI-COLOUR FADING COMPOSITION SENSIENT COSMETIC TECHNOLOGIES (FR) 2015-10-28 EP disclosed
US-20080248121-A1 MULTIPLE EMULSION CONTAINING A TENSIONING AGENT L'OREAL (FR) 2008-10-09 US disclosed
EP-1755543-A1 ANTI-COLOUR FADING COMPOSITION Lcw - Les Colorants Wackherr (FR) 2007-02-28 EP disclosed
US-20070009453-A1 Photoprotective compositions comprising an aqueous phase and a low melting point apolar wax L'OREAL (FR) 2007-01-11 US disclosed
US-7045120-B2 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers L'OREAL (FR) 2006-05-16 US disclosed
WO-2006005846-A1 ANTI-COLOUR FADING COMPOSITION LCW - LES COLORANTS WACKHERR (FR) 2006-01-19 WO disclosed
US-6955803-B2 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers L'OREAL (FR) 2005-10-18 US disclosed
US-6875426-B2 Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent L'OREAL (FR) 2005-04-05 US disclosed
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL S.A. (FR) 2004-04-15 US disclosed
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL, S.A. (FR) 2004-04-01 US disclosed
US-20030228268-A1 Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent SOCIETE L'OREAL S.A. (FR) 2003-12-11 US disclosed
US-20030215476-A1 Multiple emulsion containing a tensioning agent L'OREAL (FR) 2003-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, PCNA, DSG1 KCNK3 4292/4885KCNK9 3637/4885LMNA 224/4885
US-20040071641-A1 Photoprotective/cosmetic compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, DSG1, PCNA KCNK3 4200/4885KCNK9 3451/4885LMNA 153/4885
US-20030228268-A1 Self-tanning composition containing a tetrahydrocurcuminoid and a self-tanning agent TYR, TES, TERT KCNK3 4215/4885KCNK9 4594/4885LMNA 2995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.