SCHEMBL3900935

SCHEMBL3900935

CCC(C(=O)O)P(=O)(O)OC

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.42
MMP1 P03956 2/20 0.38
MMP2 P08253 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
MMP8 P22894 1/20 0.38
CA9 Q16790 1/20 0.38
LAP3 P28838 5/20 0.37
MMP3 P08254 1/20 0.36
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
GCLC P48506 1/20 0.33
GGH Q92820 1/20 0.32
GRM3 Q14832 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL871610 0.81 FOLH1 (0.45) FOLH1CA2LAP3GGHGRM3
SCHEMBL21059309 0.81 LAP3 (0.37) FOLH1LAP3PGK1PGK2GCLC
SCHEMBL12473689 0.81 PGK1 (0.36) FOLH1MMP1MMP2CA12CA1
SCHEMBL3908397 0.81 PPARD (0.38) FOLH1LAP3PGK1PGK2
SCHEMBL6579012 0.80 LMNA (0.38) FOLH1MMP1MMP2CA12CA1
SCHEMBL28156892 0.79 PGK1 (0.35) FOLH1MMP1MMP2CA12CA1
SCHEMBL2984496 0.78 MMP1 (0.33) FOLH1MMP1MMP2CA12CA1
SCHEMBL3471393 0.77 FOLH1 (0.40) FOLH1MMP1MMP2CA12CA1
SCHEMBL2988982 0.77 FOLH1 (0.43) FOLH1MMP1MMP2CA12CA1
SCHEMBL1960686 0.77 FOLH1 (0.54) FOLH1MMP1MMP2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1554330-B1 PARTIALLY ESTER-EXCHANGED SIPM AND PROCESS THEREWITH INVISTA TECH SARL (CH) 2009-03-11 EP claimed
EP-1615934-B1 TITANIUM CHELATE DISPERSIONS DU PONT (US) 2007-06-27 EP claimed
US-10774098-B2 Nahlsgen optical resolution method KYOTO UNIVERSITY (JP) 2020-09-15 US disclosed
US-20190225634-A1 NAHLSGEN OPTICAL RESOLUTION METHOD KYOTO UNIVERSITY (JP) 2019-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10774098-B2 Nahlsgen optical resolution method HACL2, HAO2, HPD FOLH1 1164/4885MMP1 1524/4885MMP2 4215/4885
US-20190225634-A1 NAHLSGEN OPTICAL RESOLUTION METHOD HACL2, HAO2, HPD FOLH1 1164/4885MMP1 1524/4885MMP2 4215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.