SCHEMBL392908

SCHEMBL392908

C=C(Cc1cccc(S(=O)(=O)Nc2cccc3ccccc23)c1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.61
RECQL P46063 1/20 0.59
MEN1 O00255 4/20 0.53
ALDH1A1 P00352 2/20 0.53
MAPT P10636 1/20 0.53
PTGDR2 Q9Y5Y4 1/20 0.47
MCL1 Q07820 2/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
METAP2 P50579 1/20 0.46
METAP1 P53582 1/20 0.46
NAMPT P43490 1/20 0.45
SLC16A3 O15427 2/20 0.43
PTGES2 Q9H7Z7 1/20 0.42
KDM4E B2RXH2 1/20 0.42
GSK3B P49841 1/20 0.42
ALOX12 P18054 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396990 0.83 HTR6 (0.59) KMT2AMEN1ALDH1A1
SCHEMBL393833 0.81 AKR1C3 (0.61) KMT2AMEN1ALDH1A1LMNAHTT
SCHEMBL396605 0.78 KMT2A (0.57) KMT2ARECQLMEN1ALDH1A1MAPT
SCHEMBL396887 0.78 HTR6 (0.62) KMT2AMEN1ALDH1A1
SCHEMBL398496 0.77 POLB (0.44) LMNAHTT
SCHEMBL1428546 0.76 RECQL (1.00) KMT2ARECQLMEN1ALDH1A1MAPT
SCHEMBL392888 0.75 ALDH1A1 (0.45) KMT2AALDH1A1LMNAHTTNAMPT
SCHEMBL398535 0.74 KDM4E (0.52) KMT2AMEN1ALDH1A1MAPTLMNA
SCHEMBL397724 0.73 AKR1C3 (0.48) KMT2AALDH1A1HTT
SCHEMBL398529 0.73 KMT2A (0.47) KMT2ARECQLMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed