Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.62 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | IL1RN | P18510 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396990 | 0.92 | HTR6 (0.59) | HTR6IL1RNKEAP1ERAP1HDAC1 | |
| SCHEMBL396993 | 0.90 | ALDH1A1 (0.58) | HTR6HDAC1HDAC8IKBKBGAA | |
| SCHEMBL393833 | 0.85 | AKR1C3 (0.61) | HTR6HDAC1HDAC8GAAALDH1A1 | |
| SCHEMBL396740 | 0.85 | HDAC1 (0.59) | HTR6IL1RNKEAP1ERAP1HDAC1 | |
| SCHEMBL397676 | 0.85 | HDAC1 (0.68) | HTR6IL1RNKEAP1ERAP1HDAC1 | |
| SCHEMBL398666 | 0.83 | ALDH1A1 (0.50) | KEAP1ALDH1A1POLB | |
| SCHEMBL28182428 | 0.83 | HTR6 (0.65) | HTR6PTGESIL1RNKEAP1ERAP1 | |
| SCHEMBL398544 | 0.82 | ADRA2A (0.47) | HTR6HPGDALDH1A1 | |
| SCHEMBL14425657 | 0.80 | HTR6 (0.72) | HTR6PTGESIL1RNKEAP1ERAP1 | |
| SCHEMBL27482732 | 0.80 | HTR6 (0.72) | HTR6PTGESIL1RNKEAP1ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101332-B2 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | FUJIFILM CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090246688-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| EP-2105298-A1 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | Fujifilm Corporation (JP) | 2009-09-30 | — | — | EP | disclosed |