SCHEMBL393833

SCHEMBL393833

C=C(Cc1cccc(S(=O)(=O)Nc2ccc3ccccc3c2)c1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.61
SMN1; SMN2 Q16637 3/20 0.59
LMNA P02545 2/20 0.59
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
ALDH1A1 P00352 2/20 0.53
GAA P10253 1/20 0.50
PKM P14618 1/20 0.49
PKLR P30613 1/20 0.49
PGR P06401 1/20 0.49
ATM Q13315 1/20 0.48
NR1I2 O75469 1/20 0.47
GGPS1 O95749 1/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396811 0.88 LMNA (0.62) AKR1C3SMN1; SMN2LMNAKMT2AMEN1
SCHEMBL396990 0.88 HTR6 (0.59) KMT2AMEN1ALDH1A1PKMPGR
SCHEMBL396887 0.85 HTR6 (0.62) KMT2AMEN1ALDH1A1GAAPKM
SCHEMBL392908 0.81 KMT2A (0.61) LMNAKMT2AMEN1ALDH1A1HTT
SCHEMBL396993 0.79 ALDH1A1 (0.58) KMT2AMEN1ALDH1A1GAAHDAC1
SCHEMBL397676 0.79 HDAC1 (0.68) LMNAKMT2AMEN1ALDH1A1PKM
SCHEMBL398496 0.77 POLB (0.44) AKR1C3SMN1; SMN2LMNAHTTHDAC2
SCHEMBL397573 0.77 AKR1C3 (0.56) AKR1C3SMN1; SMN2LMNAKMT2AMEN1
SCHEMBL2614387 0.76 SMN1; SMN2 (1.00) AKR1C3SMN1; SMN2LMNAKMT2AMEN1
SCHEMBL392888 0.75 ALDH1A1 (0.45) AKR1C3LMNAKMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed