Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28276079 | 0.87 | GAA (0.40) | HSD17B10CYP2C19KMT2ASMN1; SMN2LMNA | |
| SCHEMBL28146963 | 0.78 | KMT2A (0.40) | HSD17B10CYP2C19KMT2ASMN1; SMN2LMNA | |
| SCHEMBL3930136 | 0.77 | HSD17B10 (0.47) | HSD17B10CYP2C19KMT2ASMN1; SMN2LMNA | |
| SCHEMBL27957963 | 0.77 | AGTR1 (0.62) | HSD17B10CYP2C19KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6820233 | 0.75 | CYP19A1 (0.59) | KMT2ASMN1; SMN2KDM4ERCE1ALDH1A1 | |
| SCHEMBL2347898 | 0.74 | ALDH1A1 (0.39) | HSD17B10CYP2C19KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29163204 | 0.72 | ALDH1A1 (0.38) | HSD17B10CYP2C19KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29432621 | 0.72 | HSD17B10 (0.47) | HSD17B10CYP2C19KMT2ASMN1; SMN2LMNA | |
| SCHEMBL3628018 | 0.72 | POLB (0.59) | HSD17B10CYP2C19KMT2ASMN1; SMN2LMNA | |
| SCHEMBL170977 | 0.70 | AGTR1 (0.72) | HSD17B10CYP2C19KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507835-B2 | N-arylsulfonyl-3-aminoalkoxyindoles | SUVEN LIFE SCIENCES LTD. (IN) | 2009-03-24 | — | — | US | disclosed |
| US-20060173193-A1 | N-arylsulfonyl-3-aminoalkoxyindoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173193-A1 | N-arylsulfonyl-3-aminoalkoxyindoles | HTR3C, HTR3A, AANAT | HSD17B10 3722/4885CYP2C19 37/4885KMT2A 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.