Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 4/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974584 | 0.80 | MAPT (0.41) | MLYCDALDH1A1LMNANOS3NOS1 | |
| SCHEMBL4096326 | 0.77 | POLB (0.36) | MLYCDPLAUIDO1ALDH1A1LMNA | |
| SCHEMBL3973752 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2ATP53CYP3A4ALOX15 | |
| SCHEMBL4085301 | 0.77 | TRPV4 (0.38) | MLYCD | |
| SCHEMBL4078040 | 0.77 | KMT2A (0.42) | MLYCDHTR3EHTR3BPLAUHTR3A | |
| SCHEMBL11816669 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ATP53CYP3A4 | |
| SCHEMBL3972855 | 0.75 | SMN1; SMN2 (0.47) | MLYCDPLAUIDO1ALDH1A1TAAR1 | |
| SCHEMBL3971781 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ACYP3A4MAPK1 | |
| SCHEMBL4087920 | 0.73 | MEN1 (0.39) | MLYCDIDO1MEN1KMT2ANOS3 | |
| SCHEMBL3968468 | 0.73 | MAPK1 (0.40) | ALDH1A1LMNAMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016061-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | Glaxo Group Limited (GB) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007122241-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-11-01 | — | — | WO | disclosed |