Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973752 | 0.77 | ALDH1A1 (0.46) | KMT2ANOS3NOS1 | |
| SCHEMBL4096326 | 0.77 | POLB (0.36) | NPC1IDO1MLYCDNOS1 | |
| SCHEMBL11816669 | 0.77 | ALDH1A1 (0.52) | MEN1KMT2A | |
| SCHEMBL10532358 | 0.76 | NPC1 (0.59) | MEN1KMT2ANPC1 | |
| SCHEMBL3972855 | 0.75 | SMN1; SMN2 (0.47) | MEN1KMT2AIDO1MLYCD | |
| SCHEMBL3971781 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2A | |
| SCHEMBL16746567 | 0.74 | CA2 (0.43) | MEN1KMT2ALOXL2CA12CA2 | |
| SCHEMBL15484291 | 0.74 | ALDH1A1 (0.54) | MEN1KMT2AIDO1LOXL2NOS3 | |
| SCHEMBL3973730 | 0.74 | ADRA2A (0.46) | PARP10 | |
| SCHEMBL3969996 | 0.73 | MLYCD (0.43) | MEN1KMT2AIDO1MLYCDNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053448-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2009-04-30 | — | — | WO | disclosed |