Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 4/20 | 0.37 |
| ▸ | TKT | P29401 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086338 | 0.78 | — | — | |
| SCHEMBL3969996 | 0.77 | MLYCD (0.43) | MLYCD | |
| SCHEMBL4078040 | 0.71 | KMT2A (0.42) | MLYCDGPBAR1SCN9A | |
| SCHEMBL3974584 | 0.71 | MAPT (0.41) | MLYCD | |
| SCHEMBL3973752 | 0.68 | ALDH1A1 (0.46) | — | |
| SCHEMBL4096326 | 0.68 | POLB (0.36) | MLYCD | |
| SCHEMBL11816669 | 0.68 | ALDH1A1 (0.52) | — | |
| SCHEMBL2307150 | 0.66 | TRPV4 (0.48) | TRPV4MRGPRX4MAP4K4PIK3CAKCNH2 | |
| SCHEMBL29827501 | 0.66 | TRPV4 (0.48) | TRPV4MRGPRX4MAP4K4PIK3CAKCNH2 | |
| SCHEMBL3972855 | 0.66 | SMN1; SMN2 (0.47) | MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053449-A1 | THIAZOLES WHICH POTENTIATE AMPA RECEPTOR AND MEDICINAL USES THEREOF | GLAXO GROUP LIMITED (GB) | 2009-04-30 | — | — | WO | disclosed |