Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.46 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.46 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515661 | 1.00 | LMNA (0.46) | LMNABLMTSHRTHRBKMT2A | |
| SCHEMBL515689 | 1.00 | LMNA (0.46) | LMNABLMTSHRTHRBKMT2A | |
| SCHEMBL912891 | 1.00 | LMNA (0.46) | LMNABLMTSHRTHRBKMT2A | |
| SCHEMBL23722964 | 1.00 | LMNA (0.46) | LMNABLMTSHRTHRBKMT2A | |
| SCHEMBL561138 | 1.00 | LMNA (0.46) | LMNABLMTSHRTHRBKMT2A | |
| SCHEMBL23515345 | 1.00 | LMNA (0.46) | LMNABLMTSHRTHRBKMT2A | |
| SCHEMBL1578111 | 1.00 | LMNA (0.46) | LMNABLMTSHRTHRBKMT2A | |
| SCHEMBL2723355 | 1.00 | LMNA (0.46) | LMNABLMTSHRTHRBKMT2A | |
| SCHEMBL22777473 | 1.00 | LMNA (0.46) | LMNABLMTSHRTHRBKMT2A | |
| SCHEMBL17932953 | 1.00 | LMNA (0.46) | LMNABLMTSHRTHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 644 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600699-B2 | Thiosemicarbazates and uses thereof | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-04-14 | — | — | US | claimed |
| US-20250381277-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISORDERS | DANA FARBER CANCER INST INC (US) | 2025-12-18 | — | — | US | claimed |
| WO-2025242900-A1 | COACERVATE-FORMING REAGENTS AND METHODS | PARTITIONBIO LTD (GB) | 2025-11-27 | — | — | WO | claimed |
| EP-4598585-A1 | PRODUCT | Oxford University Innovation Limited (GB) | 2025-08-13 | — | — | EP | claimed |
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2025-07-08 | — | — | US | claimed |
| WO-2025136225-A1 | PROBES | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2025-06-26 | — | — | WO | claimed |
| US-12320815-B2 | Compositions and methods for enrichment and detection of ubiquitin and ubiquitin conjugates | YALE UNIVERSITY (US) | 2025-06-03 | — | — | US | claimed |
| US-20250099421-A1 | Analgesic Therapeutics Based on conjugation of Biocompatible Polymers to Ion Channel Modulators | Relevium Medical (IE) | 2025-03-27 | — | — | US | claimed |
| CN-119212728-A | Compositions and methods for treating neurological disorders | 丹娜-法伯癌症研究院 | 2024-12-27 | — | — | CN | claimed |
| EP-4472670-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISORDERS | Dana-Farber Cancer Institute, Inc. (US) | 2024-12-11 | — | — | EP | claimed |
| WO-2023150552-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISORDERS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-08-10 | — | — | WO | claimed |
| US-20230111252-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2023-04-13 | — | — | US | claimed |
| US-20220372022-A1 | COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2022-11-24 | — | — | US | claimed |
| EP-4011904-A1 | MASP INHIBITORY COMPOUNDS AND USES THEREOF | Bayer Aktiengesellschaft (DE) | 2022-06-15 | — | — | EP | claimed |
| WO-2022096394-A1 | MASP INHIBITORY COMPOUNDS AND USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-12 | — | — | WO | claimed |
| EP-3599245-A1 | IL-17A BINDING POLYPEPTIDES AND MEDICAL USES THEREOF | Dompé farmaceutici S.p.A. (IT) | 2020-01-29 | — | — | EP | claimed |
| EP-2547355-B1 | TFPI INHIBITORS AND METHODS OF USE | Baxalta GmbH (CH) | 2017-01-11 | — | — | EP | claimed |
| EP-2470672-A1 | COMPOUND | The Queen's University of Belfast (GB) | 2012-07-04 | — | — | EP | claimed |
| US-20120156691-A1 | COMPOUND | QUEEN'S UNIVERSITY OF BELFAST | 2012-06-21 | — | — | US | claimed |
| WO-2011024006-A1 | COMPOUND | QUEEN'S UNIVERSITY OF BELFAST (GB) | 2011-03-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | DNPEP, NPEPPS, PAM | LMNA 4762/4885BLM 3782/4885TSHR 1283/4885 |
| US-20230111252-A1 | THIOSEMICARBAZATES AND USES THEREOF | TST, ABAT, AADAC | LMNA 4387/4885BLM 4137/4885TSHR 255/4885 |
| US-20220372022-A1 | COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | DNPEP, NPEPPS, PAM | LMNA 4762/4885BLM 3782/4885TSHR 1283/4885 |
| US-12320815-B2 | Compositions and methods for enrichment and detection of ubiquitin and ubiquitin conjugates | STUB1, UBE3A, UBQLN1 | LMNA 1301/4885BLM 917/4885TSHR 4537/4885 |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | MET, THRB, ABAT | LMNA 4184/4885BLM 4297/4885TSHR 17/4885 |
| US-20120156691-A1 | COMPOUND | DNPEP, TMPRSS15, PEPD | LMNA 2269/4885BLM 3222/4885TSHR 4193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.