SCHEMBL400187

SCHEMBL400187

C[C@@H](OCc1ccccc1)[C@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.55
PTPN1 P18031 4/20 0.53
CDC25B P30305 4/20 0.53
PTPN2 P17706 2/20 0.53
CDC25A P30304 2/20 0.53
PPARG P37231 2/20 0.50
MMP9 P14780 2/20 0.50
MMP8 P22894 2/20 0.50
APP P05067 2/20 0.49
CTSS P25774 3/20 0.49
SYK P43405 1/20 0.49
ATM Q13315 1/20 0.49
ACE P12821 1/20 0.48
CTSL P07711 1/20 0.47
CTSB P07858 1/20 0.47
CTSK P43235 1/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12018371 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL1414710 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL2212074 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL1414711 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL400186 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL12055688 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL3449019 1.00 PPARA (0.55) PPARAPTPN1CDC25BPTPN2CDC25A
Hydrochloric Acid SCHEMBL28347451 0.99 PPARA (0.54) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL24814238 0.90 KLK5 (0.54) PPARAPTPN1CDC25BPTPN2CDC25A
SCHEMBL9545038 0.90 KLK5 (0.54) PPARAPTPN1CDC25BPTPN2CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528812-B Double amino acid-genipin derivative and preparation method and application thereof 广东工业大学 2025-06-03 CN claimed
CN-119528812-A Double amino acid-genipin derivative and preparation method and application thereof 广东工业大学 2025-02-28 CN claimed
CN-118119631-A Programmable selective acylation of polyols 南洋理工大学 2024-05-31 CN claimed
CN-111825742-B Polypeptide solid phase synthesis of CTPA as special coupling agent for amino acid ionic liquid 陈铭 2024-01-30 CN claimed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
US-4060689-A Vinylbenzyl esters of n-boc-amino acids MORTON-NORWICH PRODUCTS, INC. (US) 1977-11-29 US claimed
US-12625431-B2 EUV resist underlayer film-forming composition NISSAN CHEMICAL CORPORATION (JP) 2026-05-12 US disclosed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US disclosed
US-12612441-B2 Polypeptide and therapeutic uses thereof VITALIXIR (BEIJING) CO., LTD (CN) 2026-04-28 US disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-3127914-B1 LONG-ACTING ADRENOMEDULLIN DERIVATIVES UNIV MIYAZAKI (JP) 2025-12-17 EP disclosed
US-20250332271-A1 PROGRAMMABLE SELECTIVE ACYLATION OF POLYOLS UNIV NANYANG TECH (SG) 2025-10-30 US disclosed
US-4033998-A Vinylbenzyl ester of an N-BOC amino acid MORTON-NORWICH PRODUCTS, INC. (US) 1977-07-05 US disclosed
US-4033940-A TERMINAL CYSTINE, REARRANGEMENT TO CYCLIC DISULFIDE ARMOUR PHARMACEUTICAL COMPANY (US) 1977-07-05 US disclosed
US-4000259-A DIABETES AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-28 US disclosed
US-3991041-A GROWTH HORMONE RELEASE INHIBITOR AMERICAN HOME PRODUCTS CORPORATION (US) 1976-11-09 US disclosed
US-3988308-A (Tyr3, Tyr14)-SRIF and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-10-26 US disclosed
US-3988304-A Cyclic dodecapeptide derivatives of somatostatin and intermediates thereof AMERICAN HOME PRODUCTS CORPORATION (US) 1976-10-26 US disclosed
US-3933784-A Des-(ser13)-srif and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612441-B2 Polypeptide and therapeutic uses thereof VIP, GCG, GLS PPARA 3619/4885PTPN1 4090/4885CDC25B 3951/4885
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP PPARA 1878/4885PTPN1 4800/4885CDC25B 3478/4885
US-20250332271-A1 PROGRAMMABLE SELECTIVE ACYLATION OF POLYOLS PARG, PARN, NAAA PPARA 305/4885PTPN1 3576/4885CDC25B 1994/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 PPARA 2794/4885PTPN1 827/4885CDC25B 4815/4885
US-12625431-B2 EUV resist underlayer film-forming composition EEF1A1, ARF1, EMG1 PPARA 4500/4885PTPN1 912/4885CDC25B 2768/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 PPARA 1752/4885PTPN1 4669/4885CDC25B 2281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.